Results 81 to 90 of about 25,923,262 (305)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
How Well Does the U.S. Government Do Cost-Benefit Analysis? [PDF]
To make prudent recommendations for improving the use of cost-benefit analysis in policy settings, some measures of how well it is actually done are essential.
Hahn, Robert W., Dudley, Patrick M.
core
Estimation of Social Benefits in Cost-benefit Analysis
Theory, Methodology, Practice, 2012 While examining the cost-benefit analysis related to public policy decisions in the Hungarian and international literature, this paper is looking for the answer to the question of what the methodological principles are according to which the benefit ...
Beáta Fodor
doaj
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
The Benefit-Cost Analysis of Security Focused Regulations [PDF]
Security focused regulations have been largely exempt from the benefit-cost type of analysis required for major Federal regulations and done routinely in areas such as transportation, environment and safety.
Stuart Shapiro, Scott Farrow
core
A Cost–benefit Analysis of Continuous Assessment
Proceedings of the 7th International Conference on Computer Supported Education, 2015 Peer ...
Duch Brown, Amalia +4 more
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Immunization against Haemophilus influenzae type b in Iran; Cost-utility and cost-benefit analyses
International Journal of Preventive Medicine, 2012 Background: Haemophilus Influenzae type b (Hib) is an important cause of morbidity and mortality in children. Although its burden is considerably preventable by vaccine, routine vaccination against Hib has not been defined in the National Immunization ...
Maziar Moradi-Lakeh +2 more
doaj
The EMBO Reports, 2000 Order is the key word of science. Scientists have tried to order and explain all the phenomena of the universe. They found that the planets and stars move along predictable paths, discovered the laws of gravitation and devised formulae to describe inheritance. For them, the universe is like a clock.
openaire +2 more sources
Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus +2 more
wiley +1 more source