Results 61 to 70 of about 3,079,644 (344)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Cost-Benefit Analysis Under Uncertainty [PDF]

open access: yes
In what follows we provide a conceptually correct procedure for determining whether a risky project passes the "potential Pareto improvement" welfare criterion which forms the normative basis of cost-benefit analysis.
David A. Graham
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

The Comprehensiveness Dilemma of Cost-Benefit Analysis

open access: yesEuropean Journal of Transport and Infrastructure Research, 2013
Most project impacts on environment, climate, and health are not valued in markets or in choice situations similar to market transactions. Analysts have to go beyond revealed preferences to stated preference interviews and even to deliberative processes ...
Tore Sager
doaj   +1 more source

Cost benefit analysis vs. referenda [PDF]

open access: yes
We consider a planner who chooses between two possible public policies and ask whether a referendum or a cost benefit analysis leads to higher welfare.
Martin J. Osborne, Matthew A. Turner
core  

Cordova Psychrophiles Bio-Digester Benefit-Cost and Sensitivity Analysis [PDF]

open access: yes, 2012
Cordova is located in southcentral part of Alaska, 150 miles southeast of Anchorage, and can be accessed only by boat or plane. The average winter temperature1 varies from 17⁰ F to 28⁰ F (-8⁰ C to -2⁰ C) and the average summer temperature varies from 49⁰
Fay, Ginny   +2 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Benefit-cost analysis of participatory breeding program in Syria [PDF]

open access: yes, 2016
Participatory plant breeding is seen by several scientists as a way to overcome the limitations of conventional breeding by offering farmers the possibility of deciding which varieties better suit their needs and conditions without exposing them to any
Ceccarelli, Salvatore   +2 more
core  

Cost-benefit analysis of ecological networks assessed through spatial analysis of ecosystem services [PDF]

open access: yes, 2012
1.The development of ecological networks could enhance the ability of species to disperse across fragmented landscapes and could mitigate against the negative impacts of climate change.
Balmford   +31 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

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