Results 41 to 50 of about 657,420 (260)

COST-BENEFIT ANALYSIS OF CLIMATE CHANGE

open access: yesKöz-gazdaság, 2020
This paper examines the methodological aspect of climate change, particularly the aggregation of costs and benefits induced by climate change on individuals, societies, economies and on the whole ecosystem.
NORBERT SZIJÁRTÓ
doaj  

Cost-Benefit Analysis of the Community Patent [PDF]

open access: yesJournal of Benefit-Cost Analysis, 2011
For more than 40 years, governments and professional associations have acted, voted or lobbied against the implementation of the Community Patent (COMPAT, officially called the EU Patent). The econometric results and simulations presented in this paper suggest that, thanks to its attractiveness in terms of market size and a sound renewal fee structure,
Danguy, Jérôme   +1 more
openaire   +5 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Economic Evaluation of Health Interventions: A Critical Review

open access: yesIranian Journal of Public Health, 2022
Background: Economic evaluation is used for the optimal allocation of resources in the health sector. While a large number of economic evaluation studies have been conducted, there is less critical review of these studies.
Ali Mohammad Mosadeghrad   +2 more
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Cognition and Cost-Benefit Analysis

open access: yesSSRN Electronic Journal, 1999
Abstract Cost‐benefit analysis is often justified on conventional economic grounds, as a way of preventing inefficiency. But it is most plausibly justified on cognitive grounds—as a way of counteracting predictable problems in individual and social cognition.
openaire   +2 more sources

An Analysis of the Cost and Benefit of Search Interactions [PDF]

open access: yesProceedings of the 2016 ACM International Conference on the Theory of Information Retrieval, 2016
Interactive Information Retrieval (IR) systems often provide various features and functions, such as query suggestions and relevance feedback, that a user may or may not decide to use. The decision to take such an option has associated costs and may lead to some benefit. Thus, a savvy user would take decisions that maximises their net benefit.
Leif Azzopardi, Guido Zuccon
openaire   +5 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Incremental expenditure for hospital care associated infections [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2019
Background: Hospital care associated infections [HAI] are time varying and they substantially increase the burden for the patients, relatives, Payers, Third party Administrators and Hospital Administrators.
K.S. Sarala   +2 more
doaj  

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