Results 51 to 60 of about 27,108,475 (305)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Cost Benefit Analysis of Sports Medicine Team Coverage

open access: yesOrthopaedic Journal of Sports Medicine, 2013
Objectives: Coverage of high school athletic football by orthopaedic sports medicine specialists is considered standard of care in many localities. Taking time away from an orthopaedic practice to provide on field athletic care has potential advantages ...
Fotios P. Tjoumakaris MD   +5 more
doaj   +1 more source

Is cost–benefit analysis a foreign language? [PDF]

open access: yesQuarterly Journal of Experimental Psychology, 2017
Do people think better in a foreign language? In some ways, yes. There is considerable evidence to this effect, at least to the extent that they are less likely to rely on intuitions that can lead to serious errors. This finding reinforces, and makes more plausible, a central claim in regulatory policy, which involves the value of cost–benefit analysis.
openaire   +4 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Cost benefit analysis for failure of sewer pipelines

open access: yesMATEC Web of Conferences, 2017
Sewer pipelines failure in sewage networks can have adverse potential impacts on socio-economic aspects in any community. Due to the fact that it’s difficult to capture the relationship between the physical and economical aspects as a result of critical ...
Elmasry Mohamed   +2 more
doaj   +1 more source

The Discipline of Cost‐Benefit Analysis [PDF]

open access: yesThe Journal of Legal Studies, 2000
Abstract Cost‐benefit analysis is a general discipline, based on the use of some foundational principles, which are not altogether controversial, but have nevertheless considered plausibility. Divisiveness increases as various additional requirements are imposed.
openaire   +4 more sources

Does Mitigation Save? Reviewing cost-1 benefit analyses of disaster risk reduction [PDF]

open access: yes, 2014
The benefit-cost-ratio (BCR), used in cost-benefit analysis (CBA), is an indicator that attempts to summarize the overall value for money of a project.
Shreve, Cheney   +6 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

COST BENEFIT ANALYSIS OF COMPROMISING LEDGER SYSTEM BASED ON BLOCKCHAIN TECHNOLOGY

open access: yesBizInfo, 2018
Modern application of the blockchain technology is the center of attention of technology and economy sectors. Proper usage of blockchain is based on peer to peer (P2P) network to coordinate a worldwide, universal ledger where all transactions on the ...
Edis Mekić   +2 more
doaj   +1 more source

PRINCIPLES OF COST-BENEFIT ANALYSIS [PDF]

open access: yes
This paper summarizes the procedure for the economic evaluation of government projects and policy reforms. It begins with the social welfare function underpinnings of cost-benefit analysis including the role of distributive weights and the choice of ...
Robin Boadway
core  

Home - About - Disclaimer - Privacy