Results 41 to 50 of about 1,812,913 (288)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Journal of Sustainable Construction Materials and TechnologiesPoor road design is the bedrock for strength deformation and formation of potholes in road pavement systems. The best choice of aggregates for asphalt concrete production contributes significantly to road pavement stability, sustainability, and ...
Akinniyi Akinjide Adelani +4 more
doaj +1 more source
Calculating the Expected Value of Sample Information using Efficient Nested Monte Carlo: A Tutorial [PDF]
, 2018 Objective: The Expected Value of Sample Information (EVSI) quantifies the economic benefit of reducing uncertainty in a health economic model by collecting additional information.
Baio, Gianluca, Heath, Anna
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Evaluation of Earned Value Management-Based Cost Estimation via Machine Learning
BuildingsAccurate estimation of construction costs is of foremost importance in construction management processes. Considering the changes and unexpected situations, cost estimations should be revised during the construction process.
Gamze Yalçın +2 more
doaj +1 more source
IEEE Access, 2021 Software organization always aims at developing a quality software product using the estimated development resources, effort, and time. Global Software Development (GSD) has emerged as an essential tool to ensure optimal utilization of resources, which ...
Junaid Ali Khan +3 more
doaj +1 more source
Robust Estimation of Optical Phase Varying as a Continuous Resonant Process [PDF]
, 2013 It is well-known that adaptive homodyne estimation of continuously varying optical phase provides superior accuracy in the phase estimate as compared to adaptive or non-adaptive static estimation.
Huntington, Elanor H. +2 more
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source