Results 91 to 100 of about 1,129,710 (262)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Development of cost functions for wastewater treatment by sequential batch reactor
Journal of Environmental Engineering and Landscape ManagementSequential batch reactor is widely used for industrial wastewater treatment. To consider sequential batch reactor for biological treatment of wastewater at a specific site, it is essential to ensure economy and sustainability.
Bhaskar Sengupta +2 more
doaj +1 more source
F-Divergences and Cost Function Locality in Generative Modelling with Quantum Circuits. [PDF]
Entropy (Basel), 2021 Leadbeater C +3 more
europepmc +1 more source
On the cost-subdifferentials of cost-convex functions
, 2007 We are interested in the cost-convex potentials in optimal mass transport theory, and we show by direct and geometric arguments the equivalence between cost-subdifferentials and ordinary subdifferentials of cost-convex functions, under the assumptions A0, A1, A2, and A3W on cost functions introduced by Ma, Trudinger, and Wang.
Kim, Young-Heon, McCann, Robert J.
openaire +2 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Optimal number of imperfect repairs for deteriorating systems [PDF]
International Journal of Industrial Engineering and Production ResearchA periodic maintenance policy through either an imperfect repair or replacement is proposed for a repairable system. It is assumed that the system is subject to an inverse Gaussian degradation process.
Khatereh Rajinia, Mostafa Razmkhah
doaj
Computationally Efficient Nonlinear Model Predictive Control Using the L1 Cost-Function. [PDF]
Sensors (Basel), 2021 Ławryńczuk M, Nebeluk R.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Cost function dependent barren plateaus in shallow parametrized quantum circuits. [PDF]
Nat Commun, 2021 Cerezo M +4 more
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source