Results 11 to 20 of about 507,745 (253)
Building Analytics Tool Deployment at Scale: Benefits, Costs, and Deployment Practices
Energies, 2022 Buildings are becoming more data-rich. Building analytics tools, including energy information systems (EIS) and fault detection and diagnostic (FDD) tools, have emerged to enable building operators to translate large amounts of time-series data into ...
Guanjing Lin +4 more
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Self-employment and marriage: Costs and benefits
South African Journal of Business Management, 1996 This article highlights the effect of self-employment in a marriage by examining both the costs and possible benefits that are brought to bear when the breadwinner is in self-employment.
Cathy M. Haselau, Madhubala I. Kasiram
doaj +1 more source
Ecology and Evolution, 2021 In exploring the roles of phenotypic plasticity in the establishment and early evolution of invading species, little empirical attention has been given to the importance of correlational selection acting upon suites of functionally related plastic traits
Elizabeth P. Lacey +2 more
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Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Political Scandals as a Democratic Challenge| Hidden Traps: An Essay on Scandals — Commentary
International Journal of Communication, 2018 During scandals, observers relying on media coverage tend to attribute their perception of triggering events not to their depiction by the media but to the events depicted.
Hans Mathias Kepplinger
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Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Costs and Benefits of Transgenerational Induced Resistance in Arabidopsis
Frontiers in Plant Science, 2021 Recent evidence suggests that stressed plants employ epigenetic mechanisms to transmit acquired resistance traits to their progeny. However, the evolutionary and ecological significance of transgenerational induced resistance (t-IR) is poorly understood ...
Ana López Sánchez +4 more
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source