Results 31 to 40 of about 694,339 (306)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Benefits and costs of improving pumping efficiency
California Agriculture, 1988 Pump repair or replacement can substantially improve performance, but energy savings will depend on management of the irrigation ...
B Hanson
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
CLIMATE CHANGE – BETWEEN COSTS AND BENEFITS [PDF]
Aerul şi Apa: Componente ale Mediului, 2011 Climate change – between costs and benefits. At global and regional levels the effects of climate change start to show up. While some of the countries make efforts to alleviate these effects and to find solutions, others are facing economic or political ...
CARMEN VALENTINA RĂDULESCU +2 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Energy Innovation of Polish Local Governments
Energies, 2022 The main aim of the research is to evaluate the innovativeness of Polish municipalities in the field of energy. The study was carried out as a part of the First National Competition for the Most Innovative Local Government in Poland, taking into account ...
Sławomir Stec +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The Costs and Benefits of Consuming [PDF]
Journal of Consumer Research, 2000 Abstract Consuming is defined as behavior whereby entropy is increased in exchange for existential or experiential rewards. Existential rewards are well known—for example, the satisfaction of Maslowian needs. But experiential rewards are perhaps just as important: these refer to the temporary improvement in positive mood people ...
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source