Results 51 to 60 of about 828,584 (305)

Pollination interactions reveal direct costs and indirect benefits of plant–plant facilitation for ecosystem engineers, GitHub [R software code]

open access: yes
R code for the study "Pollination interactions reveal direct costs and indirect benefits of plant–plant facilitation for ecosystem ...
Gianalberto Losapio
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Life Years Gained and Healthcare Dollars Saved: National Economic Evidence Supporting Comprehensive Genomic Profiling as Standard of Care for Canadian Cancer Patients

open access: yesCurrent Oncology
Comprehensive genomic profiling (CGP) is a meaningful advancement in the field of oncology, enabling critical clinical decision-making regarding precision treatments that have biological rationale.
Stephanie Snow   +10 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Political Scandals as a Democratic Challenge| Hidden Traps: An Essay on Scandals — Commentary

open access: yesInternational Journal of Communication, 2018
During scandals, observers relying on media coverage tend to attribute their perception of triggering events not to their depiction by the media but to the events depicted.
Hans Mathias Kepplinger
doaj  

An Analysis of the Fourth Government Report on the Costs and Benefits of Federal Regulations [PDF]

open access: yes
This paper critically reviews the draft of the Office of Management and Budget's fourth report on the benefits and costs of federal regulation. The purpose of this analysis is to offer constructive recommendations for improving that report.
Hahn, Robert W., Litan, Robert E.
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Selection of economically rational investments through cost benefit analysis [PDF]

open access: yesEkonomski Signali, 2022
Business decision making is an act of choosing between at least two competing simultaneously available investment alternatives. Cost benefit analysis enables direct and indirect measurement of all relevant costs and benefits expected in the future based ...
Dedović Nedeljka
doaj  

Executive Summary: Weighing the Benefits and Costs of International Sanctions Against Iran

open access: yes, 2012
The executive summary of a nonpartisan report that aims to offer an objective analysis of the benefits and costs of international sanctions against ...
The Iran Project
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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