Results 51 to 60 of about 2,976,061 (298)
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Metropolitan planning Australia : urban consolidation.
Urban consolidation is a major issue on the agenda of Australian cities. The significance of this is explored in the three papers in this collection. Richard Cardew reviews the papers by Troy and Bunker, introducing some additional considerations with ...
Bunker, Raymond +3 more
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Current OncologyComprehensive genomic profiling (CGP) is a meaningful advancement in the field of oncology, enabling critical clinical decision-making regarding precision treatments that have biological rationale.
Stephanie Snow +10 more
doaj +1 more source
Lights off for arbuscular mycorrhiza: On its symbiotic functioning under light deprivation
Frontiers in Plant Science, 2016 Plants are often exposed to shade over different time scales and this may substantially affect not only their own growth, but also development and functioning of the energetically dependent organisms.
Tereza eKonvalinková, Jan eJansa
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Political Scandals as a Democratic Challenge| Hidden Traps: An Essay on Scandals — Commentary
International Journal of Communication, 2018 During scandals, observers relying on media coverage tend to attribute their perception of triggering events not to their depiction by the media but to the events depicted.
Hans Mathias Kepplinger
doaj
The Costs and Benefits of Positive Illusions
Frontiers in Psychology, 2015 Positive illusions are associated with unrealistic optimism about the future and an inflated assessment of one's abilities. They are prevalent in normal life and are considered essential for maintaining a healthy mental state, although, there are ...
Spyros eMakridakis
doaj +1 more source
The costs and benefits of providing open space in cities [PDF]
We use the monocentric model of a city to derive a simple cost-benefit rule for the optimal provision of open space. Although many researchers have investigated the value of open space in cities, few of them have compared it to the costs of providing ...
Jan Rouwendal +1 more
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