Results 51 to 60 of about 812,783 (305)

Grading Estimates of the Benefits and Costs of Federal Regulation [PDF]

I review two recent estimates of the costs and, in one case, benefits of federal regulation. The first is found in the Office of Management and Budget’s 2005 report to Congress on the benefits and costs of federal regulations (OMB 2005b).
Harrington, Winston
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Life Years Gained and Healthcare Dollars Saved: National Economic Evidence Supporting Comprehensive Genomic Profiling as Standard of Care for Canadian Cancer Patients

Current Oncology
Comprehensive genomic profiling (CGP) is a meaningful advancement in the field of oncology, enabling critical clinical decision-making regarding precision treatments that have biological rationale.
Stephanie Snow, Shantanu Banerji, Yvonne Bombard, Don Husereau, Jason Karamchandani, Eddy Nason, Pamela S. Ohashi, Gijs van Rooijen, Gilad Vainer, Cassandra Macaulay, Filomena Servidio-Italiano   +10 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Political Scandals as a Democratic Challenge| Hidden Traps: An Essay on Scandals — Commentary

International Journal of Communication, 2018
During scandals, observers relying on media coverage tend to attribute their perception of triggering events not to their depiction by the media but to the events depicted.
Hans Mathias Kepplinger
doaj  

BENEFITS, COSTS AND LIMITS OF ECONOMIC INCREASE [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
The macroeconomic situation of a nation cannot be characterized just by the equilibrium conditions of its economy, but especially by the growth level and rate of the gross domestic product or the national, total income and per inhabitant.
VĂDUVA CECILIA ELENA
doaj  

Government Analysis of the Benefits and Costs of Regulation [PDF]

Recently, Congress has shown a greater interest in assessing the economic impact of regulation. The interest is driven in part by estimates that federal regulation cost several hundred billion dollars annually.
Hahn, Robert W.
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

The Costs and Benefits of Introducing Mandatory Hygiene Regulations [PDF]

In an idealised model the costs of capital and maintenance and the resulting flow of income benefits over a period of years enables the analyst to produce computations of present values and internal rates of return that summarise the whole investment ...
Johnson, Robin, Cao, Kay
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source