Results 171 to 180 of about 76,010 (391)

Comparison of Metformin PBPK Models Incorporating Placental Transfer to Predict Fetal and Maternal Exposure. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling of placental drug transfer is an evolving tool for predicting fetal drug exposure. In this study, a pregnancy‐specific metformin PBPK model was developed, and the following four approaches were evaluated to predict metformin placental transfer: (1) perfusion‐limited model, and permeability ...
Tiley JB   +5 more
europepmc   +2 more sources

In vitro plant regenaration of tobacco (nicotiana tabaccum TAPM 26) [PDF]

open access: yes, 2010
In the present research, a reproducible procedure has been developed for efficient plant regeneration of shoot from cotyledon explants of Nicotiana tabaccum TAPM 26.
Kaya, Yilmaz
core  

The Diversity of the DNA‐Binding Landscape in the DREB/ERF Family: Focusing on Reproductive Processes in Fruit Trees With Highly Heterozygous Genome

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT DREB/ERF transcription factors play pivotal roles in plant development; however, their structural characteristics, DNA‐binding preferences, and functional roles in highly heterozygous woody plants remain insufficiently understood. Using lychee (Litchi chinensis) as a model, we identified 95 DREB/ERF genes subdivided into ten phylogenetic ...
Fengqi Wu   +9 more
wiley   +1 more source

A couple of cotyledons

open access: yes, 2022
Cotyledon is a small but diverse genus of Crassulaceae. It currently includes 16 species of perennial shrubs with paired, opposite, stiff persistent leaves and relatively large tubular, pendulous orange-red flowers. It is extreme diverse, particularly in terms of stem and leaf form and arrangement.
openaire  

Genomic signatures of heterokaryosis in the oomycete pathogen Bremia lactucae. [PDF]

open access: yes, 2019
Lettuce downy mildew caused by Bremia lactucae is the most important disease of lettuce globally. This oomycete is highly variable and rapidly overcomes resistance genes and fungicides.
Bertier, Lien D   +10 more
core  

Precision RNAi in Tomato Using Synthetic Trans‐Acting Small Interfering RNAs Derived From Minimal Precursors

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT RNA interference (RNAi) is a highly conserved gene silencing mechanism regulating gene expression at transcriptional and post‐transcriptional levels in plants. Synthetic trans‐acting small interfering RNAs (syn‐tasiRNAs) have emerged as powerful tools for highly specific and efficient gene silencing.
Ariel H. Tomassi   +8 more
wiley   +1 more source

Direct Organogenesis and Plantlet Establishment via Cotyledon Explants in Medicinally Important Herb <i>Silybum marianum</i> (L.)

open access: diamond, 2016
Mohammad Hadi Ebrahimzadeh   +4 more
openalex   +2 more sources

GmMYB4 Positively Regulates Isoflavone Biosynthesis via the GmMAPK6‐GmMYB4‐MBW Module in Soybean

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Isoflavones, a class of bioactive compounds predominantly found in leguminous plants, are largely responsible for their beneficial effects on human health. Although MYB transcription factors (TFs) are known to be crucial regulators of isoflavone biosynthesis in soybean, the precise mechanisms underlying their regulatory functions remain poorly
Changyun Yang   +12 more
wiley   +1 more source

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