Results 81 to 90 of about 6,912 (256)

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

InSAR- and PCA-Based Inversion Reveals the Surface Deformation and Earthquake Sequence in the Weiyuan-Rongxian Shale Gas Field

Remote Sensing
In recent years, the rapid expansion and development of the shale gas industry in the Sichuan Basin has coincided with a series of unexpected moderate-sized earthquakes.
Hongyu Huo, Wenbin Xu, Lei Xie, Kun Jiang, Yan Jiang   +4 more
doaj   +1 more source

Forecasting Italian seismicity through a spatio-temporal physical model: importance of considering time-dependency and reliability of the forecast

Annals of Geophysics, 2010
We apply here a forecasting model to the Italian region for the spatio-temporal distribution of seismicity based on a smoothing Kernel function, Coulomb stress variations, and a rate-and-state friction law. We tested the feasibility of this approach, and
Amir Hakimhashemi, Oliver Heidbach, Gottfried Grünthal, Dietrich Stromeyer, Mathilde B. Sørensen, Chung-Han Chan, Flaminia Catalli   +6 more
doaj   +1 more source

Deposition Rate‐Controlled Functional Evolution of p‐Type Selenium‐Alloyed Tellurium–Tellurium Oxide Films for Thin‐Film Transistors

Advanced Science, EarlyView.
This study investigates the effects of thermal deposition rate on next‐generation p‐type amorphous oxide semiconductor SeTe–TeOx films. Deposition rate governs the chemical states, microstructure, and electrical characteristics of the films, resulting in tunable device properties.
Seongmo Kang, Jeong‐Min Seo, Hyungyu Choi, Yunseo Song, Tae Woong Yoon, Tae Woong Han, Hoseong Shin, Jiyun Lee, Boseok Kang   +8 more
wiley   +1 more source

Experiments on Nonlocal Fluid‐Flow Metamaterials

Advanced Science, EarlyView.
A nonlocal fluid‐flow metamaterial composed of standard microfluidic tubes and connectors is designed. Hence, the current of the system at one position depends on the gradient of fluid flow at many other positions, leading to unusual alternating backward and forward laminar flows of water.
Ke Wang, Yi Chen, Martin Wegener
wiley   +1 more source

Coulomb Stress Changes in the 2004 Aceh Earthquake on the Mount Sibualbuali and Mount Lubukraya

Jurnal Pendidikan Fisika dan Teknologi
The great Aceh earthquake on December 26, 2004, had a magnitude of 9.2 Mw for 10 minutes with coordinates 3,316°N 95,854°E. had a tremendous impact on changes in geological conditions and disasters in Aceh and Asia, especially Southeast Asia and South Asia.
Goldberd Harmuda Duva Sinaga, Analiser Halawa, Retno Agung Prasetyo, Irving Josafat Alexander Silaban, Mardame Pangihutan Sinaga   +4 more
openaire   +2 more sources

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

Forecasting seismicity rate in the north-west Himalaya using rate and state dependent friction law

Geomatics, Natural Hazards & Risk, 2017
In this study, rate and state Coulomb stress transfer model is adopted to forecast the seismicity rate of earthquakes (MW ≥ 5) in the north-west Himalaya region within the testing period 2011–2013. Coulomb stress changes (ΔCFF), considered to be the most
Prasanta Chingtham, Sanjay K. Prajapati, Vineet K. Gahalaut, Sumer Chopra, Pareshnath Singha Roy   +4 more
doaj   +1 more source

LLMs as Representation Generators for Gradient‐Free Scientific Optimization: A Case Study in Battery Fast Charging

Advanced Science, EarlyView.
Large language models serve as representation generators for gradient‐free scientific optimization. Two complementary approaches produce executable battery‐charging policies either directly or through LLM‐designed neural representations coupled to Bayesian optimization.
Ge Lei, Ferran Brosa Planella, Sterling G. Baird, Samuel J. Cooper   +3 more
wiley   +1 more source