Results 181 to 190 of about 91,068 (301)

pH-Dependent Conformational Changes in Grb2 Monomer Reveal Different Binding Sites for Coumarin: An Insight for Small Molecule Drug Discovery. [PDF]

ACS Omega
Casteluci G, Dias RVR, Tedesco JA, Gouveia LE, de Oliveira ASGR, Caruso ÍP, de Melo FA.   +6 more
europepmc   +1 more source

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, Volume 13, Issue 33, 15 June 2026.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Light‐Controlled Peptide Self‐Assembly: From Physicochemical Principles to Emerging Biomedical Applications

Aggregate, Volume 7, Issue 6, June 2026.
This review surveys recent advances in light‐controlled peptide self‐assembly for the design of smart soft matter. It summarizes the underlying physicochemical principles, including thermodynamic control for reshaping free‐energy landscapes, and nonequilibrium control to produce kinetically trapped states and dissipative structures.
Lidong Chen, Yanan Cui, Yuxuan Han, Chuqiang Ke, Wendi Jiang, Rui Yu, Lingling Kang, Kai Liu   +7 more
wiley   +1 more source

Coumarin-Thiourea Hybrids: Structural Features Governing CA Inhibition and Antiproliferative Effects. [PDF]

Int J Mol Sci
Fuentes-Aguilar A, Colombo R, González-Bakker A, Puerta A, Merino-Montiel P, Montiel-Smith S, Vega-Báez JL, Giovannuzzi S, Nocentini A, Fernández-Bolaños JG, Supuran CT, Padrón JM, López Ó.   +12 more
europepmc   +1 more source

Stimuli‐Responsive Hydrogels for Optical Applications: Mechanisms, Architectures, and Translational Challenges

Aggregate, Volume 7, Issue 6, June 2026.
The review discusses stimuli‐responsive hydrogels as soft optical materials that translate physical, chemical, and biological cues into refractive‐index, scattering, birefringence, diffraction, and transparency changes. It examines major stimulus classes and photonic architectures for biosensing, waveguiding, adaptive lenses, smart windows, and therapy.
Andrés Bernal‐Ballén, Alexandr Dejneka, Oleg Lunov   +2 more
wiley   +1 more source

Photolyzable Polymer Brushes: Subtractive 3D Structuring of Surfaces Using Water and Light. [PDF]

Angew Chem Int Ed Engl
Kalmer H, Sbordone F, Do PT, Mundsinger K, Kayas H, Jones RT, Mendhi J, Dargaville TR, Harkin DG, Michalek L, Nelson A, Frisch H.   +11 more
europepmc   +1 more source

Ion‐Pairing and Counterion Effects in Contemporary Photochemistry

Angewandte Chemie Novit, Volume 2, Issue 2, June 2026.
Ion‐pairing and counterion effects have emerged as fundamental yet underexplored determinants of photochemical behavior. Far from inert, counterions, and Coulombic interactions modulate excited‐state dynamics, quenching efficiencies, emission, and catalytic pathways.
Matthias Schmitz, Christoph Kerzig
wiley   +1 more source

The evolution of heat shock protein 90 C-terminal inhibitors: From novobiocin to potential clinical candidates. [PDF]

Cell Stress Chaperones
Jiang X, Blagg BSJ.
europepmc   +1 more source

A Selective Phenyl Azo Acetate Substrate for Enhanced Carbonic Anhydrase Functional Analysis

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Carbon dioxide (CO2) sequestration is a key strategy for mitigating climate change, and biocatalytic approaches offer sustainable, cost‐effective alternatives to chemical and physical methods. Carbonic anhydrases (CAs) efficiently catalyse the reversible hydration of CO2 to bicarbonate, yet their large‐scale application is constrained by ...
Justinas Babinskas, Inga Matijošytė
wiley   +1 more source

Coumarin-Amino Acid Hybrids Used as Possible Multifactorial Anti-Inflammatory Agents. [PDF]

Int J Mol Sci
Fotopoulos I, Hadjipavlou-Litina D.
europepmc   +1 more source