Results 181 to 190 of about 94,849 (289)

Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis

eFood, Volume 7, Issue 3, June 2026.
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng, Yanqun Luo, Ying Gao, Yi Su, Haiping Xue, Tao Wu   +5 more
wiley   +1 more source

Torsion-Induced π-Conjugation Offers an Approach to Small Coumarin-Based Color-Changing Fluorescent Sensors of Esterase Activity. [PDF]

Chemistry
Oronova A, Bobnock G, Begoyan VV, Tanasova M.   +3 more
europepmc   +1 more source

Exploring the Antifungal Potential of the Brown Macroalga Hormophysa triquetra: Morphological Disruptions and Structural Changes in Plant Pathogens

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Extracts of Hormophysa triquetra showed antifungal activity with marked hyphal deformities in Fusarium oxysporum and Alternaria alternata. Light microscopy and SEM confirmed structural alterations despite unchanged radial growth. Cucumber assays validated reduced disease incidence, linked to fatty‐acid–rich metabolites detected by GC–MS.
Shazia Bibi, Samir Jaoua, Mohammad A. Al‐Ghouti, Nabil Zouari, Mohammed H. Abu‐Dieyeh   +4 more
wiley   +1 more source

Photocaged Chloroquine Derivatives for the Light-Dependent Inhibition of Autophagy in Cancer Stem Cells. [PDF]

ACS Chem Biol
Alonso-Manresa S, Serra C, Muñoz L, Bataller M, Garcia-Mayea Y, Lleonart Pajarin ME, Garcia Prats B, Mancilla Zamora S, Diaz Riascos ZV, Llebaria A, Josa-Culleré L.   +10 more
europepmc   +1 more source

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source

Plasma metabolomic signatures in children with autism spectrum disorder and their modulation following a gluten-free modified ketogenic diet. [PDF]

BMC Psychiatry
Singh R, Shah A, Jain N, Shah H, Rawal R.   +4 more
europepmc   +1 more source

Catalytic Enantioselective Synthesis of Conformationally Stable C(sp2)−C(sp3) Naphthocoumarin Atropisomers

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
The enantioselective synthesis of naphthocoumarin adducts via a tandem organocatalytic 1,4‐addition/decarboxylation delivers excellent control over a newly forged stereocenter and yields configurationally stable synclinal atropisomers. The process features broad substrate scope and scalability, and its structural and mechanistic foundations are ...
M. Chiara Cabua, Davide Moi, Emanuele Cocco, Valentina Onnis, Enrico Podda, David J. Aitken, Armando Carlone, Renzo Luisi, Enrica Tuveri, Drew F. Parsons, Francesco Secci   +10 more
wiley   +1 more source

Sequence-Modulated Active Tripeptide Condensates for Tandem Catalysis. [PDF]

Angew Chem Int Ed Engl
Han H, Song S, Wang J, Ivanov T, Zhou D, Su H, Landfester K, Cao S.   +7 more
europepmc   +1 more source

Design and fabrication of a zero-bias visible light photodetector based on a coumarin-derived Schiff base thin film. [PDF]

RSC Adv
Sharma I, K A J, Shil S, Kekuda D, Anil Kumar NV.   +4 more
europepmc   +1 more source

Coumarin-Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents. [PDF]

Chem Biol Drug Des
Matar IK, Zaki MEA, Muhammad ZA, Awwad DA, Al-Hussain SA, Matta CF, Kassab RM.   +6 more
europepmc   +1 more source