Results 31 to 40 of about 91,068 (301)

Coumarin Communication Along the Microbiome-Root-Shoot Axis.

Trends in Plant Science, 2020
Plants shape their rhizosphere microbiome by secreting root exudates into the soil environment. Recently, root-exuded coumarins were identified as novel players in plant-microbiome communication.
Max J J Stassen, S. Hsu, C. Pieterse, Ioannis A. Stringlis   +3 more
semanticscholar   +1 more source

Coumarin sulfonamide derivatives: An emerging class of therapeutic agents

Heterocyclic Communications, 2020
Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which is a core and integral part of different therapeutic scaffolds and analogues.
Irfan Ali, Rubab Laila, Rehman Mishbah Ur, Anjum Rukhsana, Ullah Sami, Marjana Mahwish, Qadeer Saba, Sana Sadia   +7 more
doaj   +1 more source

Molecular Modelling Based on TD-DFT Applied to UV Spectra of Coumarin Derivatives

Walisongo Journal of Chemistry, 2023
The optimization of geometry and electronic transition of seven coumarin derivatives for sunscreen activity have been conducted using Orca. DFT methods is applied to find optimum geometry and parameter data is measured like bond length and bond angle. TD-
Mokhamat Ariefin, Rokiy Alfanaar
doaj   +1 more source

Coumarin: A natural solution for alleviating inflammatory disorders

Current Research in Pharmacology and Drug Discovery
Coumarin, a naturally occurring compound found in various plants, has a rich history of use in traditional medicine. Recent research has highlighted its anti-inflammatory properties, positioning it as a promising candidate for treating inflammatory ...
F. Saadati, Amir Modarresi Chahardehi, Negar Jamshidi, N. Jamshidi, Darioush Ghasemi   +4 more
semanticscholar   +1 more source

Coumarin Derivatives in Inflammatory Bowel Disease

Molecules, 2021
Inflammatory bowel disease (IBD) is a non-communicable disease characterized by a chronic inflammatory process of the gut and categorized into Crohn’s disease and ulcerative colitis, both currently without definitive pharmacological treatment and cure ...
L. D. Di Stasi
semanticscholar   +1 more source

Transcriptomic profiling of Melilotus albus near-isogenic lines contrasting for coumarin content

Scientific Reports, 2017
Coumarin and its derivatives are widely used as fragrances in industrial products and have medical value. The goal of the present study was to discover genes and pathways related to coumarin biosynthesis in Melilotus albus using transcriptome analysis ...
Kai Luo, Fan Wu, Daiyu Zhang, Rui Dong, Zhichao Fan, Rui Zhang, Zhuanzhuan Yan, Yanrong Wang, Jiyu Zhang   +8 more
doaj   +1 more source

NMR-Based Metabolomics to Analyze the Effects of a Series of Monoamine Oxidases-B Inhibitors on U251 Cells

Biomolecules, 2023
Alzheimer’s disease (AD) is a typical progressive neurodegenerative disorder, and with multiple possible pathogenesis. Among them, coumarin derivatives could be used as potential drugs as monoamine oxidase-B (MAO-B) inhibitors.
Zili Guo, Jinping Gu, Miao Zhang, Feng Su, Weike Su, Yuanyuan Xie   +5 more
doaj   +1 more source

In silico molecular docking studies and MM/GBSA analysis of coumarin-carbonodithioate hybrid derivatives divulge the anticancer potential against breast cancer

Beni-Suef University Journal of Basic and Applied Sciences, 2020
There are many biomarkers associated with breast cancer. Higher expression of PIK3CA (Phosphoinositide 3-kinase Cα), in its upregulated form, is associated with Hr+ and Her2− breast cancer; therefore, many drugs were synthesized against this protein to ...
Shridhar Pattar, Shakeel Ahmed Adhoni, C. Kamanavalli, Suresh S. Kumbar   +3 more
semanticscholar   +1 more source

Upcycling Water Pollutants Into Long‐Chain Polymers via Synergistic Interfacial Dechlorination and Organic Radical Stabilization

Angewandte Chemie, EarlyView.
HEO‐regulated electronic structure drives nonradical PI activation, promoting ETP‐mediated polymerization of 4CP into high‐molecular‐weight products with enhanced surface enrichment. Concurrent dechlorination occurs via radical coupling and •OHads attack, enabling efficient carbon retention and selective product evolution at the liquid–solid interface.
Ziwei Yao, Yidi Chen, Penghui Shao, Jian Liu, Xiaodan Wang, Kunsheng Hu, Xubiao Luo, Nanqi Ren, Xiaoguang Duan   +8 more
wiley   +2 more sources

Increased intestinal permeability and bile acid accumulation via inhibition of the FXR-SHP pathway contribute to coumarin-induced systemic inflammation

Microbiology Spectrum
Coumarin causes severe poisoning in animals, affecting the development of agriculture and animal husbandry. Coumarin induces hepatotoxicity, but the inflammatory mechanism of coumarin is unclear.
Na Shou, Dandan Wu, Qi Wang, Ping Huang, Qiwen Lin, Senao Hou, Keyi Fu, Wenqian Xu, Jiyu Zhang, Zunji Shi   +9 more
doaj   +1 more source