Results 31 to 40 of about 65,551 (284)
The antitumor effects of mitochondria-targeted 6-(nicotinamide) methyl coumarin
Open Life Sciences, 2016 Cancer is the second leading cause of death worldwide. Traditional antitumor drugs exhibit severe cytotoxic and side effects. Lung cancer needs new and more effective treatment approaches. Coumarin derivatives can act on various tumor cells and show anti-
Wang Huanan, Yao Ming, Xu Wenqing
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Coumarin Derivatives Inhibit ADP-Induced Platelet Activation and Aggregation
Molecules, 2022 Coumarin was first discovered in Tonka bean and then widely in other plants. Coumarin has an anticoagulant effect, and its derivative, warfarin, is a vitamin K analogue that inhibits the synthesis of clotting factors and is more widely used in the ...
Ping-Hsun Lu +8 more
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Apoptosis Induction by New Coumarin Derivatives in a Mice Model of Breast Cancer [PDF]
Archives of Razi Institute, 2023 In the last decades, numerous studies have focused on the search for new agents to suppress the growth of cancer cells. In this study, we investigated the effect of two novel synthetic coumarin derivatives, namely 2-amino-4-(4-(2-hydroxyethoxy)-3 ...
Mehran Mesgari Abbasi +8 more
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Anti-biofilm activities of coumarin as quorum sensing inhibitor for Porphyromonas gingivalis
Journal of Oral Microbiology, 2022 Porphyromonas gingivalis is a keystone pathogen in periodontitis, a biofilm-mediated infection disease. This research aimed to investigate the effect of coumarin on P. gingivalis biofilm formation. We detected the antimicrobial effect on P.
Zhiyan He +6 more
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Coumarin-pi, a new antioxidant coumarin derivative from Paxillus involutus
, 2019 Chemical investigation of Paxillus involutus lead to the isolation of a new coumarin derivative coumarin-pi (1), and three known compounds (2-4). The structure of the new compound was elucidated by interpretation of 1D and 2D NMR data.
Jun Zhang (48506) +5 more
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, 2019 Three novel Ru(II) complexes, namely, (RuCl2[La][DMSO]2)·H2O (Ru1), (RuCl2[Lb][DMSO]2) (Ru2), and (RuCl2[Lc][DMSO]2) (Ru3), which respectively contain 3-(2′-benzimidazolyl)coumarin (La), 3-(2′-benzimidazolyl)-7-fluoro-coumarin (Lb), and 3-(2 ...
Bei-Bei Shi +11 more
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Coumarin sulfonamide derivatives: An emerging class of therapeutic agents
Heterocyclic Communications, 2020 Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which is a core and integral part of different therapeutic scaffolds and analogues.
Irfan Ali +7 more
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Molecular Modelling Based on TD-DFT Applied to UV Spectra of Coumarin Derivatives
Walisongo Journal of Chemistry, 2023 The optimization of geometry and electronic transition of seven coumarin derivatives for sunscreen activity have been conducted using Orca. DFT methods is applied to find optimum geometry and parameter data is measured like bond length and bond angle. TD-
Mokhamat Ariefin, Rokiy Alfanaar
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Coumarin-1,2,3-triazole hybrid derivatives: Green synthesis and DFT calculations
, 2019 A series of new 1,2,3-triazole-coumarin hybrid system are synthesized from the click reaction between 3-azido coumarin and different aromatic terminal alkyne derivatives in a green manner.
Alireza Foroumadi (526325) +2 more
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Transcriptomic profiling of Melilotus albus near-isogenic lines contrasting for coumarin content
Scientific Reports, 2017 Coumarin and its derivatives are widely used as fragrances in industrial products and have medical value. The goal of the present study was to discover genes and pathways related to coumarin biosynthesis in Melilotus albus using transcriptome analysis ...
Kai Luo +8 more
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