Results 11 to 20 of about 91,068 (301)

Discovery of Novel Coumarin Derivatives as Potential Dual Inhibitors against α-Glucosidase and α-Amylase for the Management of Post-Prandial Hyperglycemia via Molecular Modelling Approaches

open access: yesMolecules, 2022
Coumarin derivatives are proven for their therapeutic uses in several human diseases and disorders such as inflammation, neurodegenerative disorders, cancer, fertility, and microbial infections.
Shashank M. Patil   +8 more
doaj   +2 more sources

Synthetic coumarin derivatives with anticoagulation and antiplatelet aggregation inhibitory effects

open access: yesMedicinal Chemistry Research, 2023
Thrombosis is the leading cause of illness and mortality worldwide, posing a serious risk to human health and life. Because antithrombotic drugs can prevent the beginning and progression of thrombotic disorders, they are essential in the management of ...
Triveena M. Ramsis   +2 more
semanticscholar   +1 more source

An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities

open access: yesInternational Journal of Molecular Sciences, 2020
Privileged structures have been widely used as an effective template for the research and discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and it can be found in a considerable number of plants as well as in some ...
Francesca Annunziata   +4 more
semanticscholar   +1 more source

Molecular Insights into Coumarin Analogues as Antimicrobial Agents: Recent Developments in Drug Discovery

open access: yesAntibiotics, 2022
Simple Summary Coumarins are a large family of benzopyrones, and more than 1300 coumarins have been reported to date. Natural, as well as synthetic, coumarins have demonstrated a diverse activity spectrum.
R. Cheke   +11 more
semanticscholar   +1 more source

Interaction of 3-(1H-tetrazol-5-yl) Coumarin With Bovine Serum Albumin and Calf Thymus DNA: Deciphering the Mode of Binding by In Vitro Studies [PDF]

open access: yesAvicenna Journal of Medical Biochemistry, 2022
Background: Coumarins comprise a large family of heterocyclic compounds with a benzo-a-pyrone moiety. Objectives: This study aimed to analyze the binding affinity of 3-(1H-tetrazol-5-yl) coumarin to bovine serum albumin (BSA) and calf thymus DNA (Ct ...
Javad Sargolzaei   +2 more
doaj   +1 more source

Coumarins in Food and Methods of Their Determination

open access: yesFoods, 2020
Coumarin is a natural product with aromatic and fragrant characteristics, widespread in the entire plant kingdom. It is found in different plant sources such as vegetables, spices, fruits, and medicinal plants including all parts of the plants—fruits ...
Mirjana Lončar   +6 more
doaj   +1 more source

Coumarin derivatives as promising antibacterial agent(s)

open access: yes, 2021
Nowadays, bacterial infections epitomize significant health threats globally with an increased morbidity and mortality. Most contemporary antibacterial agents are resisted by pathogenic bacteria - the multidrug resistant (MDR) bacterial strains arising ...
C. R. Sahoo   +7 more
semanticscholar   +1 more source

Effects of Coumarin on Amylase Activity, Electrolyte Leakage and Growth of Wheat (Triticum aestivum L.), Barley (Hordeum vulgare L.) and Sesame (Sesamum indicium L.) [PDF]

open access: yesAgrotechniques in Industrial Crops
Coumarin as a secondary metabolite widely found in plant species. Coumarin with a strong inhibitory effect on germination will be a good alternative for weed control. The mechanism of inhibition effects of coumarin has not yet been well understood.
Masoud Haidarizadeh   +2 more
doaj   +1 more source

Protective Effects of 3-benzoyl-7-hydroxy Coumarin on Liver of Adult Rat Exposed to Aluminium Chloride

open access: yesActa Chimica Slovenica, 2021
In this study, the effects of 3-benzoyl-7-hydroxy coumarin molecule on mineral and antioxidant enzymes were investigated in rat liver exposed to oxidative stress with aluminium chloride (AlCl3). Adult male Wistar albino rats were divided into four groups
Ahmet Ozkaya, Kenan Türkan
doaj   +1 more source

Coumarin–Tetrapyrrolic Macrocycle Conjugates: Synthesis and Applications

open access: yesMolecules, 2017
This review covers the synthesis of coumarin–porphyrin, coumarin–phthalocyanine and coumarin–corrole conjugates and their potential applications. While coumarin–phthalocyanine conjugates were obtained almost exclusively by tetramerization of coumarin ...
Ana F. R. Cerqueira   +3 more
doaj   +1 more source

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