Results 51 to 60 of about 43,230 (246)
Advanced Science, EarlyView.Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan +8 more
wiley +1 more source
4-Hydroxy-3-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2H-chromen-2-one
Acta Crystallographica Section E, 2009 A new chalcone of the coumarin, C21H18O7, containing an annulated α-pyrone ring, was obtained by condensation of the borate complex of acyl(hydroxy)coumarin with trimethoxybenzaldehyde.
Lassaad Mechi +3 more
doaj +1 more source
Advanced Science, EarlyView.Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng +7 more
wiley +1 more source
Recent advances in the biosynthesis of coumarin and its derivatives
Green Chemical EngineeringCoumarin and its derivatives, presenting in many organisms (plants, fungi, and bacteria), are critical metabolites composed of fused benzene and α-pyrone rings.
Yusong Zou, Yuxi Teng, Joy Li, Yajun Yan
doaj +1 more source
DFT Calculations and Mesophase Study of Coumarin Esters and Its Azoesters
Crystals, 2018 Two groups of coumarin derivatives, 4-methyl-2-oxo-2H-chromen-7-yl 4-alkoxybenzoates (coumarin esters), In, and 4-methyl-2-oxo-2H-chromen-7-yl 4-(2-(4-alkoxyphenyl)diazenyl) benzoates (coumarin azoesters), IIn, were synthesized and investigated for their
M. Hagar, H.A. Ahmed, O.A. Alhaddadd
doaj +1 more source
One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy
Advanced Science, EarlyView.This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu +8 more
wiley +1 more source
Advanced Science, EarlyView.A new fluorescent probe, MitoQUMA, brings mitochondrial RNA G‐quadruplexes (mtRNA G4s) into view in live cells. This tool reveals that excessive mtRNA G4 formation halts mitochondrial RNA granule (MRG) assembly, opposite to the phase‐separation role of cytoplasmic RNA G4s. A chemical genetic screen further identifies a Wnt/β‐catenin–GRSF1–mtRNA G4 axis
Gui‐Xue Tang +7 more
wiley +1 more source
Coumarin structure as a lead scaffold for antibacterial agents - molecular docking
Biologica Nyssana, 2016 Coumarins owe their class name to “Coumarou”, the vernacular name of the tonka bean (Dipteryx odorata Willd, Fabaceae), from which coumarin was isolated in 1820.
Veselinović, J.B. +3 more
doaj +1 more source
Biomolecules, 2020 Accumulating evidence demonstrates that the risk of osteoporotic fractures increases in patients with diabetes mellitus. Thus, diabetes-induced bone fragility has recently been recognized as a diabetic complication. As the fracture risk is independent of
Eun-Jung Lee +8 more
doaj +1 more source
A PILOT STUDY FOR THE USE OF COUMARIN-480 TO ENHANCE FINGERMARKS
Studia Universitatis Babes-Bolyai Chemia, 2019 A new alternative super glue post-treatment method for the enhancement of fingermarks over two different non-porous surfaces including glass slides and high-density polyethylene (HDPE) sheets have been investigated.
Muhammad YASEEN +4 more
doaj +1 more source