Results 41 to 50 of about 1,529,859 (297)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Common European Framework of Reference: Transcending perspectives
Moderna Språk, 2022 Stressing a balanced and constrained interplay between the individual and the collective and tending towards transdisciplinarity as a consequence, a socio-cognitive perspective prevails in second language acquisition research (Larsen-Freeman 2018 ...
Ariadna Strugielska +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Наукові записки НаУКМА: Юридичні науки, 2021 The present case commentary is focused on cases concerning the so-called Maidan events of 2013-2014. The commentary suggests that the cases at issue underline existence of the long-standing systemic and structural problems within the domestic legal ...
Pavlo Pushkar
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
THE EUROPEAN COUNCIL AND ITS ROLE IN PROMOTING AND DEFENDING HUMAN RIGHTS IN THE EUROPEAN AREA [PDF]
Strategii Manageriale, 2014 The Council of Europe advocates freedom of expression and of the media, freedom of assembly, equality, and the protection of minorities. It has launched campaigns on issues such as child protection, online hate speech, and the rights of the Roma, Europe ...
Ion, POPESCU, Cosmin-Ionut, ENESCU
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European Convention for the Protection of Human Rights and Fundamental Freedoms
Українське Pелігієзнавство, 1996 EUROPEAN CONVENTION ON THE PROTECTION OF HUMAN RIGHTS AND FUNDAMENTAL FREEDOMS Signed on November 4, 1950 by the representatives of the first member states of the Council of Europe, is the main document of the Council of ...
Editorial board of the Journal
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The European Convention on Human Rights and Counter-Terrorism [PDF]
, 2004 No part of the world has more experience with terrorism than Europe. The response of the Council of Europe through the jurisprudence of the European Court of Human Rights to its experience of terrorism may therefore assist in the ongoing battle against ...
Hedigan, John
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Protecting IDPs in Europe [PDF]
Forced Migration Review, 2008 Over the past decade the 47-member Council of Europehas put a considerable amount of effort into promoting theGuiding Principles.
Corien Jonker
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