Results 51 to 60 of about 3,750,272 (307)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Revista de Derecho Político, 2018 Resumen: Estudio de la regulación constitucional y normativa del Consejo de Estado español, desde su reconocimiento constitucional en 1978, pasando por la ley orgánica 3/1980, hasta la reforma acaecida por ley orgánica 3/2004, en los ámbitos referidos a ...
José Manuel Vera Santos
doaj +1 more source
Three questions about “informal regulation” [PDF]
, 2018 In the grand debates of international law, the jus ad bellum is often proclaimed dead, and just as often praised as the “cornerstone” of the contemporary legal order.
Tams, Christian J.
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Donor Diversity through Public Matching Funds [PDF]
, 2012 New York State is considering a system of public campaign financing for state elections similar to the one New York City uses for municipal elections. In that system, the city puts up six dollars in public matching funds for each of the first $175 that a
Brendan Glavin +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Is diversity changing religious education? Religion, diversity and education in today’s Europe [PDF]
, 2009 The study of religious diversity as part of public education has become an important issue in recent times across Europe and in the wider international arena.
Jackson, Robert
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
For the Benefit of All: Strategic Recommendations to Enhance the State's Role in the Integration of Immigrants in Illinois (Report of the New Americans Policy Council, Year One) [PDF]
, 2002 On November 19, 2005, Illinois Governor Rod Blagojevich signed the New Americans Executive Order, a first-in-the-nation attempt to adopt a coherent, strategic, and proactive state government approach to integrate the rapidly growing immigrant population ...
Louise Cainkar
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