Results 101 to 110 of about 544,131 (290)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
BMC PsychologyUnlike alphabetic language, Chinese is an ideographic language that does not contain spaces between words. Chinese readers must develop unique segmentation strategies for word recognition and reading comprehension.
Mingjing Chen +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A qualitative study into the psychological effects of acting work among Australian-based actors
Australian Journal of PsychologyObjective Acting practices can leave actors with unresolved emotions that may impact their daily life. The current study aims to describe how actors practice their craft, and how these practices are perceived in relation to their psychosocial wellbeing ...
Genevieve Brott +2 more
doaj +1 more source
Counselling in schools: what the research tells us, what we need to find out [PDF]
, 2008 Paper presented to the BACP event 'A celebration of school-based counselling', held at the The Pavilion, Llandrindod Wells, Powysin, Wales on Thursday 1 October ...
Cooper, Mick
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Counselling Foster Parents [PDF]
, 1968 My interest in this topic is the result of having been a foster parent for a period of one year for a group home for emotionally disturbed teenage boys. When my husband and I undertook this project, we had been married for two years and had one daughter ...
Thompson, Airdrie
core +1 more source