Results 181 to 190 of about 279,737 (286)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Counselling within South Africa's public health system: Mental healthcare users' experiences. [PDF]

J Public Health Afr
Lappeman M, Aaron C, Botha R, Cader-Mokoa N, Firfirey-Brijlal N, Ismail F, Leibrandt V, Nell J, van Dyk C.   +8 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Parental Decision-Making Process in Termination of Pregnancy for Congenital Heart Disease: From the Multidisciplinary Perinatal Council of a Turkish Tertiary Center. [PDF]

Diagnostics (Basel)
Oktem A, Ceylan M, Golbasi H.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Effectiveness of a combined online and in-person training model in improving village health workers' counselling quality and infant and young child feeding practices: a mixed-methods study in rural China. [PDF]

J Glob Health
Wu Q, Zhu X, Wang X, Meng N, Li J, Peng A, Zhang Y, Chang S.   +7 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Early onset gastrointestinal cancers - a needs analysis. [PDF]

Front Oncol
Keohane N, Deac O, Reynolds J, Elliott J, Narayanasamy R, Donohoe C, Gallagher D, Warner N, Enright C, Smyth E, Larkin J, McCormick P, Kelly ME, Harrold E, Lowery M.   +14 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Mental Health Support Services in Universities: A Dyadic Exploration of Students' and Counsellors' Perspectives. [PDF]

Healthcare (Basel)
Kamarudin NN, Muhamad Tamyez PF, Wan Abd Manan WKA, Piaralal SK, S Senathirajah ARB, Sivagurunathan PD, Ng PK, Qin P, Sivagurunathan R.   +8 more
europepmc   +1 more source