Results 31 to 40 of about 45,936 (263)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
On the Counter-Rotating Tori and Counter-Rotating Parts of the Kerr Black Hole Shadows
UniverseWe review some aspects of accretion disks physics, spacetime photon shell and photon orbits, related to retrograde (counter-rotating) motion in Kerr black hole (BH) spacetimes. In this brief review, we examine the counter-rotating components of the Kerr BH shadow boundary, under the influence of counter-rotating accretion tori, accreting flows and ...
Daniela Pugliese, Zdenek Stuchlík
openaire +1 more source
Discovery of counter-rotating gas in the galaxies NGC 1596 and 3203 and the incidence of gas counter-rotation in S0 galaxies [PDF]
Monthly Notices of the Royal Astronomical Society, 2006 8 pages, including 1 table and 2 figures. Accepted for publication in MNRAS. Version with full resolution figures available at http://www-astro.physics.ox.ac.uk/~bureau/pub_list ...
Bureau, M, Chung, A
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Effects of neutral beam injection on tearing mode stability: insights from hybrid simulations
Nuclear FusionIn tokamak plasmas, tangential neutral beam injection (NBI) produces (a large fraction of) circulating energetic ions (CEIs) and induces plasma toroidal rotation, both of which play an important role in the stability of tearing mode (TM).
Sizhe Duan, Xiang Zhu, Huishan Cai
doaj +1 more source
The Paleo-Orientations of Northwestern Borneo and Adjacent South China Sea Basins
Indonesian Journal on Geoscience, 2014 DOI: 10.17014/ijog.v7i2.136Limited paleomagnetic data from West Kalimantan and southwestern Sarawak appear to indicate counter-clockwise (CCW) rotation of over 50 degrees during Cenozoic.
H. D. Tjia
doaj +1 more source