Results 61 to 70 of about 2,940 (212)

Nanofiber adsorbents for high productivity continuous downstream processing [PDF]

open access: yes, 2015
An ever increasing focus is being placed on the manufacturing costs of biotherapeutics. The drive towards continuous processing offers one opportunity to address these costs through the advantages it offers.
Dods, S   +7 more
core   +1 more source

Analytical, Preparative, and Industrial-Scale Separation of Substances by Methods of Countercurrent Liquid-Liquid Chromatography

open access: yesMolecules, 2020
Countercurrent liquid-liquid chromatographic techniques (CCC), similar to solvent extraction, are based on the different distribution of compounds between two immiscible liquids and have been most widely used in natural product separations.
Artak A. Kostanyan   +2 more
doaj   +1 more source

Leonurine: A Multifaceted Bioactive Alkaloid—From Pharmacological Mechanisms to Clinical Translation: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley   +1 more source

Countercurrent chromatography of proteins using aqueous two-phase systems

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The biotechnology industry requires high - capacity protein manufacturing processes that retain protein functionality.
Bourton, Emma Catherine
core  

LC/MS Guided Isolation of Alkaloids from Lotus Leaves by pH-Zone-Refining Counter-Current Chromatography

open access: yesMolecules, 2011
The traditional methods used in natural product separation primarily target the major components and the minor components may thus be lost during the separation procedure.
Rui-Lin Hu   +5 more
doaj   +1 more source

Research on the degradation mechanism, product effects and optimization strategy of the tributyl phosphate solvent system in the PUREX process

open access: yesSmart Molecules, Volume 4, Issue 1, March 2026.
This paper focuses on reviewing the degradation mechanisms of tributyl phosphate and its diluents, the analytical technique suitable for characterizing degradation products, and the impact of degradation products on the post‐treatment process, offering a theoretical foundation and technical insights in optimizing the plutonium uranium redox extraction ...
Tian Lan, Jiaxin Liu, Yi Liu
wiley   +1 more source

Preparative Purification of Anti-Proliferative Diarylheptanoids from Betula platyphylla by High-Speed Counter-Current Chromatography

open access: yesMolecules, 2016
A simple and rapid method using high-speed counter-current chromatography (HSCCC), along with bioassay-guided fractionation based on the anti-proliferative activity against renal and colon cancer cells, has been developed for the preparative separation ...
Namki Cho   +5 more
doaj   +1 more source

Seasonal Variation of Off‐Flavours in a Full‐Scale Recirculating Aquaculture System Rearing Rainbow Trout Oncorhynchus mykiss—A Case Study

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 1, February 2026.
ABSTRACT Recirculating aquaculture system (RAS) is a promising strategy for economically and environmentally sustainable fish farming. Unfortunately, microorganisms in an RAS may produce off‐flavours that accumulate in fish flesh and reduce consumer attraction for aquaculture‐produced fish. Traditionally, geosmin (GSM) and 2‐methylisoborneol (MIB), the
Petra Camilla Lindholm‐Lehto
wiley   +1 more source

The hydrodynamics of countercurrent chromatography in J-type centrifuges

open access: yes, 2002
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Countercurrent chromatography (CCC) is an advanced liquid-liquid extraction technique that purifies chemical components from complex mixtures.
Wood, Philip Leslie
core  

Uncovering the Key Factors Influencing Phytochemical and Phytopharmacological Properties During Medicinal Plant Processing

open access: yeseFood, Volume 7, Issue 1, February 2026.
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley   +1 more source

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