Results 61 to 70 of about 1,586,292 (228)

Enantioseparation using a counter-current bioreactor [PDF]

, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The potential of countercurrent chromatography (CCC) as a small footprint bioreactor/separator for manufacture of enantiopure chiral molecules was explored,
Grudzien, Lukasz
core   +6 more sources

Asymmetric Dialysis: Truly Unified and Simultaneous Single‐Pass Concentration and Buffer Exchange

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1814-1824, July 2026.
Asymmetric dialysis, a novel one‐step continuous process combining ultrafiltration and diafiltration, achieves high product concentrations (up to 200 g/L) with low pressures and reduces buffer consumption by 75% compared to conventional methods. This sustainable, low‐cost technology demonstrates significant potential for integration into continuous ...
Ujwal Patil, Michelle Chen, Irina Ramos, Jon Coffman   +3 more
wiley   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

An integrated continuous downstream process with real‐time control: A case study with periodic countercurrent chromatography and continuous virus inactivation

Biotechnology and Bioengineering, 2020
Integrated continuous downstream processes with process analytical technology offer a promising opportunity to reduce production costs and increase process flexibility and adaptability.
Anton Löfgren, Joaquín Gomis-Fons, N. Andersson, B. Nilsson, L. Berghard, Christine Lagerquist Hägglund   +5 more
semanticscholar   +1 more source

Experimentally Overcoming the Limitations of Methanol Synthesis From Syngas by Sorption Enhancement

Chemical Engineering &Technology, Volume 49, Issue 6, June 2026.
A deep analysis of the sorption‐enhanced reaction process (SERP) for methanol synthesis from CO2/H2 syngas with the experimental study of many parameters. ABSTRACT Methanol is an excellent candidate as a low carbon footprint fuel for the energy transition.
Enrico Antonuccio, Frédéric Bornette, Guillaume Aubert, David Edouard, Pascal Fongarland   +4 more
wiley   +1 more source

(6,9)-6″-(4″-Hydroxybenzoyl)-Roseoside, a New Megastigmane Derivative from and its Effect on Hepatic Glucose-6-phosphatase

Natural Product Communications, 2012
A new megastigmane derivative, (6 R ,9 S )–6′-(4″-hydroxybenzoyl)-roseoside ( 1 ) and two known compounds, the biflavoneagathisflavone ( 2 ) and 4-hydroxy-benzoic acid ( 3 ) were isolated and purified from leaves and stems of Ouratea polyantha Engl ...
Jairo Bermúdez, María Rodríguez, Masahisa Hasegawa, Freddy González-Mujica, Sandra Duque, Yoichiro Ito   +5 more
doaj   +1 more source

Cedrela fissilis Vell. Inner Bark: LC–MS/MS‐Based Chemical Profiling and Toxicological Effects

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
ABSTRACT Investigating the mechanistic toxicity of plant extracts is essential for safety assessment. The predictive toxicological effects of Cedrela fissilis were evaluated, and LC–MS/MS‐based chemical profiling was performed. The hydroethanolic extract (HeECf) and ethyl acetate (EA) fraction were assessed in multimodel systems with different levels ...
Thainá Pereira da Silva Cabral, Emanuel Victor dos Santos Nunes, Viviani de Brito Massad Gomes da Silva, Fhelipe Jolner Souza de Almeida, Douglas Lisboa Ramalho, Jadyellen Rondon Silva, Anderson de Oliveira Souza, Maria Cristina Fuzari Bezerra, Ian Castro‐Gamboa, Helder Lopes Teles, Mayara Peron Pereira   +10 more
wiley   +1 more source

Identification and In Vitro Cytotoxic Evaluation of (E)‐Nerolidol From Piper mollicomum Kunth Essential Oil in Breast and Lung Cancer Cell Lines

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
This study integrates chemical characterization and biological evaluation of Piper mollicomum. Ethanolic and dichloromethanic extracts and the leaf essential oil were analyzed, revealing a sesquiterpene‐rich composition with (E)‐nerolidol as the major compound.
Letícia Barbosa Santos, Raquel Speziali Aroeira Marques dos Santos, Nayara Couto Moreira, Gustavo Pereira Cosenza, Paula Mendonça Leite, Elaine Maria de Souza‐Fagundes, Mônica Cristina de Oliveira, Izabella Thaís da Silva, Rachel Oliveira Castilho   +8 more
wiley   +1 more source

Sample Preparation and Separation of Lignans by Liquid Chromatography

Journal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT Lignans are important phytochemicals found mostly in the resins of coniferous trees, but are also introduced into human diets through foods such as sesame seeds and extra‐virgin olive oil. They are pharmacologically interesting mainly because of their antioxidant activities, and they have also been shown to have cytotoxic and antimicrobial ...
Miikka Paloluoto, Susanne K. Wiedmer
wiley   +1 more source

Isolation of anthocyanins by high-speed countercurrent chromatography and application of the color activity concept to different varieties of red grape pomace from Macedonia. [PDF]

, 2013
Anthocyanins of Macedonian grape pomace from three varieties “Pinot noir”, “Merlot” and “Vranec” were isolated by high speed countercurrent chromatography.
Bogeva, Elena, Velickovska, Sanja Kostadinovic, Mirhosseini, Hamed   +2 more
core   +1 more source