Results 41 to 50 of about 2,940 (212)

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Isolation of Phenolics from by Combined Counter-current Chromatography and Gel-Filtration

Natural Product Communications, 2014
Nine phenolic compounds, quercetin, epi -catechin, catechin, 4-hydroxybenzoic acid, kaempferol 3- O -β-glucopyranoside, quercetin 3- O -β-glucopyranoside, quercetin 3- O -6″- trans -coumaroyl-β-glucoside, kaempferol 3- O -β-rutinoside and quercetin 3- O -
Fernanda das Neves Costa, Marcos Daniel da Silva, Ricardo Moreira Borges, Gilda Guimarães Leitão   +3 more
doaj   +1 more source

Separation of avermectin components from Streptomyces avemitilis extraction using high-speed counter-current chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2013
Three compounds of antibiotics-avermectins from fertilizing product of Streptomyces avemitilis are achieved by high-speed counter-current chromatography (HSCCC) with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (6:
Su Weike, Hou Zhuoni, Liang Xianrui
doaj   +1 more source

Experimentally Overcoming the Limitations of Methanol Synthesis From Syngas by Sorption Enhancement

Chemical Engineering &Technology, Volume 49, Issue 6, June 2026.
A deep analysis of the sorption‐enhanced reaction process (SERP) for methanol synthesis from CO2/H2 syngas with the experimental study of many parameters. ABSTRACT Methanol is an excellent candidate as a low carbon footprint fuel for the energy transition.
Enrico Antonuccio, Frédéric Bornette, Guillaume Aubert, David Edouard, Pascal Fongarland   +4 more
wiley   +1 more source

Isolation of Anthocyanins by high-speed countercurrent chromatography and application of the color activity concept to different varieties of red grape pomace from Macedonia [PDF]

, 2013
Anthocyanins of Macedonian grape pomace from three varieties “Pinot noir”, “Merlot” and “Vranec” were isolated by high speed countercurrent chromatography.
Kostadinovic Velickovska, Sanja, Bogeva, Elena, Velickovska, Sanja Kostadinovic, Mirhosseini, Hamed   +3 more
core   +1 more source

Isolation of phenolic compounds from Rheedia longifolia by high-speed countercurrent chromatography

Rodriguésia
Rheedia longifolia is a species of the Clusiaceae family, popularly known as bacupari. Pharmacological studies conducted by our group revealed that the raw methanolic extract of its leaves, along with its fractions, induces both inflammatory and ...
Ana Luiza Rangel Bérenger, Flávia da Cunha Camillo, Lavínia de Carvalho Brito, Maria Auxiliadora Coelho Kaplan, Maria Raquel Figueiredo   +4 more
doaj   +1 more source

Cedrela fissilis Vell. Inner Bark: LC–MS/MS‐Based Chemical Profiling and Toxicological Effects

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
ABSTRACT Investigating the mechanistic toxicity of plant extracts is essential for safety assessment. The predictive toxicological effects of Cedrela fissilis were evaluated, and LC–MS/MS‐based chemical profiling was performed. The hydroethanolic extract (HeECf) and ethyl acetate (EA) fraction were assessed in multimodel systems with different levels ...
Thainá Pereira da Silva Cabral, Emanuel Victor dos Santos Nunes, Viviani de Brito Massad Gomes da Silva, Fhelipe Jolner Souza de Almeida, Douglas Lisboa Ramalho, Jadyellen Rondon Silva, Anderson de Oliveira Souza, Maria Cristina Fuzari Bezerra, Ian Castro‐Gamboa, Helder Lopes Teles, Mayara Peron Pereira   +10 more
wiley   +1 more source

Identification and In Vitro Cytotoxic Evaluation of (E)‐Nerolidol From Piper mollicomum Kunth Essential Oil in Breast and Lung Cancer Cell Lines

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
This study integrates chemical characterization and biological evaluation of Piper mollicomum. Ethanolic and dichloromethanic extracts and the leaf essential oil were analyzed, revealing a sesquiterpene‐rich composition with (E)‐nerolidol as the major compound.
Letícia Barbosa Santos, Raquel Speziali Aroeira Marques dos Santos, Nayara Couto Moreira, Gustavo Pereira Cosenza, Paula Mendonça Leite, Elaine Maria de Souza‐Fagundes, Mônica Cristina de Oliveira, Izabella Thaís da Silva, Rachel Oliveira Castilho   +8 more
wiley   +1 more source

Sample Preparation and Separation of Lignans by Liquid Chromatography

Journal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT Lignans are important phytochemicals found mostly in the resins of coniferous trees, but are also introduced into human diets through foods such as sesame seeds and extra‐virgin olive oil. They are pharmacologically interesting mainly because of their antioxidant activities, and they have also been shown to have cytotoxic and antimicrobial ...
Miikka Paloluoto, Susanne K. Wiedmer
wiley   +1 more source

A Protocol for Characterizing Comprehensive Two‐Dimensional Liquid Chromatography Systems

Journal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT Comprehensive two‐dimensional liquid chromatography (LC × LC) is an effective strategy to increase peak capacity and improve separation performance for complex samples, offering a valuable alternative to conventional one‐dimensional liquid chromatography (1D‐LC).
Megane K. Aebischer, Marie Pardon, Clémence Gadot, Katia Arena, Niklas Carstensen, Michael Laemmerhofer, Paola Dugo, Francesco Cacciola, Luigi Mondello, Morgan Sarrut, Deirdre Cabooter, Sabine Heinisch, Davy Guillarme   +12 more
wiley   +1 more source