Results 41 to 50 of about 530,368 (183)

The kidney antifibrotic effects of 5,7,3′,4′,5′-pentamethoxyflavone from Bauhinia championii in streptozotocin-induced diabetic rats: in vivo and in vitro experiments

Pharmaceutical Biology, 2023
Context The antidiabetic effects of flavonoids have been reported, but it is still unclear whether 5,7,3′,4′,5′-pentamethoxyflavone, isolated from Bauhinia championii Benth.
Jialin Li, Xiaocui Huang, Kailun He, Suzhen Wu   +3 more
doaj   +1 more source

Toward Robust Optimal Control of Chromatographic Separation Processes With Controlled Flow Reversal

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 3, September 2026.
ABSTRACT Column liquid chromatography is an important technique applied in the production of biopharmaceuticals, specifically for the separation of biological macromolecules such as proteins. When setting up process conditions, it is crucial that the purity of the product is sufficiently high, even in the presence of perturbations in the process ...
Dominik H. Cebulla, Christian Kirches, Andreas Potschka   +2 more
wiley   +1 more source

Anion‐Exchange Membrane Chromatography for the Separation of Empty and Full Adeno‐Associated Viral Capsids

Biotechnology Journal, Volume 21, Issue 8, August 2026.
Graphical Abstract and Lay Summary The anion‐exchange membrane elution chromatography for the separation of empty and full AAVs is explored and optimized. The role played by important parameters like flowrate, gradient slope, membrane loading, and feed residence time is studied in detail.
Luca Ossi, Samuele Delfino, Helena Marie, Michael Schulte, Mattia Sponchioni   +4 more
wiley   +1 more source

Isolation of phenolic compounds from Rheedia longifolia by high-speed countercurrent chromatography

Rodriguésia
Rheedia longifolia is a species of the Clusiaceae family, popularly known as bacupari. Pharmacological studies conducted by our group revealed that the raw methanolic extract of its leaves, along with its fractions, induces both inflammatory and ...
Ana Luiza Rangel Bérenger, Flávia da Cunha Camillo, Lavínia de Carvalho Brito, Maria Auxiliadora Coelho Kaplan, Maria Raquel Figueiredo   +4 more
doaj   +1 more source

Separation of avermectin components from Streptomyces avemitilis extraction using high-speed counter-current chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2013
Three compounds of antibiotics-avermectins from fertilizing product of Streptomyces avemitilis are achieved by high-speed counter-current chromatography (HSCCC) with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (6:
Su Weike, Hou Zhuoni, Liang Xianrui
doaj   +1 more source

Understanding Mass Spectrometry: From Ion Generation to Spectral Interpretation

Journal of Mass Spectrometry, Volume 61, Issue 8, August 2026.
ABSTRACT This tutorial provides a structured introduction to mass spectrometry (MS), with particular emphasis on electrospray ionization (ESI)–based measurements. It is intended to support researchers from chemistry and related disciplines in developing a coherent understanding of MS principles, instrumentation, and data interpretation.
Arnold Steckel, Dávid Papp, Gitta Schlosser   +2 more
wiley   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, Volume 13, Issue 38, 9 July 2026.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Isolation of Phenolics from by Combined Counter-current Chromatography and Gel-Filtration

Natural Product Communications, 2014
Nine phenolic compounds, quercetin, epi -catechin, catechin, 4-hydroxybenzoic acid, kaempferol 3- O -β-glucopyranoside, quercetin 3- O -β-glucopyranoside, quercetin 3- O -6″- trans -coumaroyl-β-glucoside, kaempferol 3- O -β-rutinoside and quercetin 3- O -
Fernanda das Neves Costa, Marcos Daniel da Silva, Ricardo Moreira Borges, Gilda Guimarães Leitão   +3 more
doaj   +1 more source

Asymmetric Dialysis: Truly Unified and Simultaneous Single‐Pass Concentration and Buffer Exchange

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1814-1824, July 2026.
Asymmetric dialysis, a novel one‐step continuous process combining ultrafiltration and diafiltration, achieves high product concentrations (up to 200 g/L) with low pressures and reduces buffer consumption by 75% compared to conventional methods. This sustainable, low‐cost technology demonstrates significant potential for integration into continuous ...
Ujwal Patil, Michelle Chen, Irina Ramos, Jon Coffman   +3 more
wiley   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source