Results 21 to 30 of about 1,586,292 (228)

Modern countercurrent chromatography

, 2008
Countercurrent chromatography (CCC) is experiencing a renaissance and offers a variety of benefits for preparative chromatography. This technique is useful for the isolation of natural products and can eliminate some of the problems associated with solid-phase adsorbents.
Marston, Andrew, Hostettmann, Kurt
core   +3 more sources

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification. [PDF]

Biotechnol Bioeng
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Wang Z, Javidanbardan A, Behboudi A, Zydney AL.   +3 more
europepmc   +2 more sources

Synthesis and Application of Zearalenone Substitute Cyclododecyl 2,4-Dihydroxybenzoate

Liang you shipin ke-ji, 2021
Cyclododecyl 2,4-dihydroxybenzoate (CDHB) is very similar to zearalenone (ZEN) in terms of size,shape,steric conformation and property.It is commonly used as a template of ZEN for the preparation of molecularly imprinted polymers.N’N′-carbonyldiimidazole
HAN Yang-ying, WANG Jun, LIU Hu-ju, SUN Chang-po   +3 more
doaj   +1 more source

Enantioseparation of two antifungal azole drugs by analytical countercurrent chromatography using sulfobutyl ether-β-cyclodextrin as chiral selector.

Journal of Chromatography A, 2023
This study reports a successful enantioseparation of two antifungal drugs, Ketoconazole and Voriconazole, using countercurrent chromatography (CCC) with synthesized sulfobutyl ether-β-cyclodextrin (SBE-β-CD) as chiral selector.
Huiyun Qiu, Hai-Ping Xiang, Meng-Yi Wen, Song-Lin Chen, Junchao Zhu, Sheng-Qiang Tong   +5 more
semanticscholar   +1 more source

Advanced modelling and visualisation of liquid-liquid separations of complex sample components, with variable phase distribution and mode of operation [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research is about liquid-liquid chromatography modelling.
De Folter, Jozefus Johannes Martinus
core   +7 more sources

The isolation of (6S, 9S)-cyclo (prolylvalyl) from marine actinomycete, by use of high speed contercurrent chromatography [PDF]

Journal of the Serbian Chemical Society, 2002
The marine actinomycete B 1758 came from the actinomycete collection of the Alfred Wegener Institute for Polar and Marine Research in Bremerhafen Germany. 1.079 g of raw extract was obtained by fermentation.
Šmelcerović Andrija A., Schiebel Mirko, Đorđević Siniša M.   +2 more
doaj   +1 more source

Application of commercial ultrafiltration membranes for protein purification by high performance countercurrent membrane purification (HPCMP). [PDF]

Biotechnol Prog
Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Mohammadzadehmarandi A, Heller N, Ahmadimashhadi M, Petrone J, Marchand N, Darvishmanesh S, Zhang K, Menegatti S, Zydney AL.   +8 more
europepmc   +2 more sources

Profiling and Isolation of Ten Rare Branched-Chain Alkylresorcinols in Quinoa

Molecules, 2023
Alkylresorcinols (∑ARs) are bioactive lipid compounds predominantly found in cereals. These amphiphilic compounds exist in a high structural diversity and can be divided into two main groups, i.e., 5-alkylresorcinols (ARs) and 2-methyl-5-alkylresorcinols
Tim Hammerschick, Walter Vetter
doaj   +1 more source

Isolation of Two New Phenolic Glycosides from Castanopsis chinensis Hance by Combined Multistep CC and HSCCC Separation and Evaluation of Their Antioxidant Activity

Molecules, 2023
The characteristics of high polarity and susceptibility to oxidation in phenolic glycosides increase the difficulty of their separation from natural products.
Ya-Feng Wang, Ping Lin, Yong-Lin Huang, Rui-Jie He, Bing-Yuan Yang, Zhang-Bin Liu   +5 more
doaj   +1 more source

Continuous Affinity Purification of Adeno-Associated Virus Using Periodic Counter-Current Chromatography

Pharmaceutics, 2022
Replacing batch unit operations of biopharmaceuticals by continuous manufacturing is a maturing concept, with periodic counter-current chromatography (PCC) favoured to replace batch chromatography.
João P. Mendes, Magnus Bergman, Anita Solbrand, Cristina Peixoto, Manuel J. T. Carrondo, Ricardo J. S. Silva   +5 more
doaj   +1 more source