Countercurrent chromatography of proteins using aqueous two-phase systems [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The biotechnology industry requires high - capacity protein manufacturing processes that retain protein functionality.
Bourton, Emma Catherine
core +7 more sources
Prediction of Elution Profiles in Countercurrent Chromatography With a Linear Loss of Stationary Phase. [PDF]
A common challenge in reliably predicting elution profiles in countercurrent chromatography using the ProMISE2 software is a persistent loss of stationary phase (i.e., bleeding). This drawback can be overcome by a simple calibration method in the case of linear bleeding.
Rüttler F, Ormos R, Vetter W.
europepmc +2 more sources
The hydrodynamics of countercurrent chromatography in J-type centrifuges [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Countercurrent chromatography (CCC) is an advanced liquid-liquid extraction technique that purifies chemical components from complex mixtures.
Wood, Philip Leslie
core +7 more sources
Advanced modelling and visualisation of liquid-liquid separations of complex sample components, with variable phase distribution and mode of operation [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research is about liquid-liquid chromatography modelling.
De Folter, Jozefus Johannes Martinus
core +7 more sources
Recent Progress on Countercurrent Chromatography Modeling [PDF]
Yun Wei, Yoichirô Itô
exaly +2 more sources
Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification. [PDF]
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Wang Z +3 more
europepmc +2 more sources
Synthesis and Application of Zearalenone Substitute Cyclododecyl 2,4-Dihydroxybenzoate
Cyclododecyl 2,4-dihydroxybenzoate (CDHB) is very similar to zearalenone (ZEN) in terms of size,shape,steric conformation and property.It is commonly used as a template of ZEN for the preparation of molecularly imprinted polymers.N’N′-carbonyldiimidazole
HAN Yang-ying +3 more
doaj +1 more source
The isolation of (6S, 9S)-cyclo (prolylvalyl) from marine actinomycete, by use of high speed contercurrent chromatography [PDF]
The marine actinomycete B 1758 came from the actinomycete collection of the Alfred Wegener Institute for Polar and Marine Research in Bremerhafen Germany. 1.079 g of raw extract was obtained by fermentation.
Šmelcerović Andrija A. +2 more
doaj +1 more source
Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]
The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core +6 more sources
Profiling and Isolation of Ten Rare Branched-Chain Alkylresorcinols in Quinoa
Alkylresorcinols (∑ARs) are bioactive lipid compounds predominantly found in cereals. These amphiphilic compounds exist in a high structural diversity and can be divided into two main groups, i.e., 5-alkylresorcinols (ARs) and 2-methyl-5-alkylresorcinols
Tim Hammerschick, Walter Vetter
doaj +1 more source

