Results 51 to 60 of about 5,459 (278)

Content analysis of the official documents on the turnover of counterfeit medicines in Ukraine in 2017–2020

open access: yesФармацевтичний журнал, 2021
The purpose of the work was to conduct a content analysis of the orders of the State Medicines Service on the prohibition of the circulation of counterfeit medicines and the information messages of law enforcement agencies in 2017–2020.
S. О. Lebed, A. S. Nemchenko
doaj   +1 more source

Coaxial Melt Electrowriting

open access: yesAdvanced Materials Technologies, EarlyView.
Coaxial melt electrowriting is established to produce dual‐property microfibers with diameters spanning 1.6–29.2 µm. Stable coaxial laminar flow is preserved under electrohydrodynamic thinning, enabling controlled binary and gradient material switching within individual continuous fibers.
Patrick C. Hall   +11 more
wiley   +1 more source

Turning Water Into a Tool: From Degradation Pathways to Functional Engineering in Halide Perovskites

open access: yesAdvanced Materials Technologies, EarlyView.
Water exhibits a threshold‐dependent dual role in lead halide perovskites, acting either as a degradation trigger or as a powerful tool for defect passivation, recrystallization, and structural engineering. This review discusses how controlled water‐mediated interactions govern stability, dimensionality, and optoelectronic performance, providing ...
Raphaella T. S. Gonçalves   +4 more
wiley   +1 more source

Immediate Organic Room‐Temperature Phosphorescence in Programmable Luminescent Tags Enabled by Oxygen‐Free Fabrication

open access: yesAdvanced Materials Technologies, EarlyView.
Programmable luminescent tags based on organic room‐temperature phosphorescence are shown to be governed by oxygen incorporation during fabrication. Oxygen‐free processing enables immediate phosphorescence activation, controlled thermal preconditioning, and tunable activation doses.
Lucy Winkler   +2 more
wiley   +1 more source

Medical,economical and social risk of counterfeit drugs [PDF]

open access: yes, 2018
Pharmaceuticals are pivotal for the health and well-being of populations. Their consumption and access can be related to a double-edged sword: on one hand, they ease the manifestation of disease but on the other hand, if they are inappropriately used ...
Rina, Daniel
core  

Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification

open access: yesAngewandte Chemie, EarlyView.
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond   +7 more
wiley   +2 more sources

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Direct Regioselective para‐Fluorination via I(I)/I(III) Catalysis

open access: yesAngewandte Chemie, EarlyView.
A direct, para‐selective fluorination by I(I)/I(III) catalysis is disclosed that does not require substrate pre‐functionalization. This strategy leverages the Leonard link inherent to phenylpropanoate and phenylpropanamides to promote a spirocyclization/para‐selective sequence. The C3‐side chain maps onto a range of common drug scaffolds and allows the
Christoph Roblick   +5 more
wiley   +2 more sources

Anticounterfeit packaging technologies

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2010
Packaging is the coordinated system that encloses and protects the dosage form. Counterfeit drugs are the major cause of morbidity, mortality, and failure of public interest in the healthcare system.
Ruchir Y Shah   +2 more
doaj   +1 more source

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