Results 71 to 80 of about 5,459 (278)

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

open access: yesAdvanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang   +13 more
wiley   +1 more source

The rise of counterfeit medication: an emerging threat?

open access: yesJournal of the Pakistan Medical Association
Madam, The definition of health is far more complex than initially imagined. As per the World Health Organisation (WHO), the “health” is defined as complete physical, mental, and social well-being instead of simply the absence of any disease.1 In the ...
Muhammad Omar Larik
doaj   +1 more source

Real‐Time Multicolor Fluorescence Microscopy via Cross‐Channel Acquisition and Deep‐Learning‐Based Inference

open access: yesAdvanced Intelligent Discovery, EarlyView.
Sequential multicolor fluorescence imaging in dynamic microsystems is constrained by acquisition speed and excitation dose. This study introduces a real‐time framework to reconstruct spectrally separated channels from reduced cross‐channel acquisitions (frames containing mixed spectral contributions).
Juan J. Huaroto   +3 more
wiley   +1 more source

Uncertainty‐Guided Selective Adaptation Enables Cross‐Platform Predictive Fluorescence Microscopy

open access: yesAdvanced Intelligent Discovery, EarlyView.
Deep learning models often fail when transferred to new microscopes. A novel framework overcomes this by selectively adapting the early layers governing low‐level image statistics, while freezing deep layers that encode morphology. This uncertainty‐guided approach enables robust, label‐free virtual staining across diverse systems, democratizing ...
Kai‐Wen K. Yang   +9 more
wiley   +1 more source

Sleep Disturbances in Adults With Tuberous Sclerosis Complex: Influences of Treatment and Clinical Features

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Tuberous sclerosis complex (TSC) is a genetic condition with multisystem neurocutaneous signs, including hamartomas, epilepsy, and neuropsychological difficulties. Although sleep disorders are increasingly recognized in TSC, they remain poorly described in adults.
Kirstin A. Risgaard   +6 more
wiley   +1 more source

Substandard, Spurious, Falsely-Labelled, Falsified and Counterfeit (SSFFC) Drugs: Time to Take a Bitter Pill [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2016
Substandard, Spurious, Falsely-Labelled, Falsified and Counterfeit (SSFFC) drugs are an emerging public health concern in India. With one of the huge pharmaceutical sectors in the world, India has a varied prevalence of SSSFC drugs ranging from 0.04% to ...
Geetha Mani   +2 more
doaj  

ECONOMIC AND LEGAL ASPECTS AGAINST CONTROLLING GOODS TURNOVER

open access: yesBaltic Journal of Economic Studies, 2019
The purpose of this article is to describe the content of the economic and legal bases of counteraction to the circulation of counterfeit goods. Using systemic and formal-logical methods, the amount of economic losses is outlined and the magnitudes of ...
Ruslan Fyl, Galina Luk'yanova
doaj   +1 more source

Guidelines for field surveys of the quality of medicines: a proposal. [PDF]

open access: yes, 2009
Paul Newton and colleagues propose guidelines for conducting and reporting field surveys of the quality of ...
Catherine Goodman   +78 more
core   +1 more source

Identification Of Counterfeit Drugs Using Near-infrared Spectroscopy. [PDF]

open access: yes, 2015
This work was aimed at the investigation of the use of near-infrared spectroscopy (NIRS) for the identification of counterfeit drugs. The identification is based on the comparison of the NIR spectrum of a sample with typical spectra of the authentic drug
Pasquini, C, Scafi, S H
core   +3 more sources

Potential conflicts in the fight against counterfeit drugs [PDF]

open access: yes
This analysis looks at the best way to deal with the proliferation of fake drugs, and considers the conflict that arises when government agencies aim to reduce the harmful effects of the fake medicine trade while the pharmaceutical firms seek profit ...
Luis Currais, Berta Rivera, Paolo Rungo
core  

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