Results 71 to 80 of about 1,044,680 (278)

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

Angewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

Tackling Counterfeit Drugs: The Challenges and Possibilities. [PDF]

Pharmaceut Med, 2023
Pathak R, Gaur V, Sankrityayan H, Gogtay J.   +3 more
europepmc   +1 more source

GAN‐LSTM‐3D: An efficient method for lung tumour 3D reconstruction enhanced by attention‐based LSTM

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Three‐dimensional (3D) image reconstruction of tumours can visualise their structures with precision and high resolution. In this article, GAN‐LSTM‐3D method is proposed for 3D reconstruction of lung cancer tumours from 2D CT images. Our method consists of three phases: lung segmentation, tumour segmentation, and tumour 3D reconstruction. Lung
Lu Hong, Mohammad Hossein Modirrousta, Mohammad Hossein Nasirpour, Mohammadreza Mirshekari Chargari, Fardin Mohammadi, Seyed Vahid Moravvej, Leila Rezvanishad, Mohammadreza Rezvanishad, Ivan Bakhshayeshi, Roohallah Alizadehsani, Imran Razzak, Hamid Alinejad‐Rokny, Saeid Nahavandi   +12 more
wiley   +1 more source

DEVELOPMENT OF QUANTITATIVE HPTLC-DENSITOMETRY METHODS FOLLOWING A MODEL APPROACH FOR TRANSFER OF TLC SCREENING METHODS FOR PHARMACEUTICAL PRODUCTS OF METFORMIN HCL, POTASSIUM CLAVULANATE, CAFFEINE, FLUOXETINE HCL, AND GABAPENTIN

Studia Universitatis Babes-Bolyai Chemia, 2017
Transfer of thin-layer chromatography Global Pharma Health Fund Minilab kit protocols for detecting counterfeit drugs in pharmaceutical products in the field to quantitative high-performance TLC (HPTLC)-densitometry methods was carried out for potassium
Kaitlin NGUYEN, Danhui ZHANG, Joseph SHERMA   +2 more
doaj   +1 more source

Diffusion of counterfeit medical products in a developing country: Empirical evidence for Suriname [PDF]

Based on detailed shipping figures of Suriname’s main harbour in Paramaribo, we estimate the total shipments (in kilograms) of original and counterfeit medical products for 1996-2008 across five product categories. Using various time series techniques,
Franses, Ph.H.B.F., Lede, M.
core  

Counterfeit anti-infective drugs.

, 2006
The production of counterfeit or substandard anti-infective drugs is a widespread and under-recognised problem that contributes to morbidity, mortality, and drug resistance, and leads to spurious reporting of resistance and toxicity and loss of ...
Newton, Paul, Day, Nicholas, Fernández, FM, Day, NP, White, NJ, White, Nicholas, Green, MD, Newton, PN   +7 more
core   +1 more source

Quality of antidiabetic medicines in 13 sub-Saharan African countries: a cross-sectional surveyResearch in context

EClinicalMedicine
Summary: Background: The burden of diabetes is rising dramatically in low- and middle-income countries. The menace of substandard and falsified drugs constitutes a major hazard that compromises healthcare.
Marie Antignac, Roland N'Guetta, Philippe Henri Secretan, Bernard Do, Meo Stephane Ikama, Jean Bruno Mipinda, Ibrahim Ali Toure, Jean Laurent Takombe, Yves Lubenga, Mouhamadoul Mounir Dia, El Bou Isselmou Boukhary Ould, Maxwell Dalaba, Naby Moussa Balde, Amadou Kake, Ely Cheikh Ibrahima Sy, Pauline Cavagna, Marie Cécile Perier, Eugène Sobngwi, Pr Badara Cisse, Christian Boitard, J.P. Empana, I. Bara Diop, Maimouna Ndour Mbaye, Xavier Jouven   +23 more
doaj   +1 more source

Identification of Counterfeit Drugs by Community Pharmacists in Lagos State [PDF]

, 2007
Purpose: The problem of fake and counterfeit drugs is real and constitutes a major threat to the health and safety of the Nigerian population. A descriptive study was carried out to assess the methods of identification of counterfeit drugs by community ...
Osemwenkha, S, Eke, E U, Odili, V U, Okeri, H A   +3 more
core   +1 more source

Early diagnosis of axial spondyloarthritis is associated with less long‐term spinal structural damage: a longitudinal analysis of the Swiss Clinical Quality Management in rheumatic diseases registry

Arthritis &Rheumatology, Accepted Article.
Objectives The Assessment of SpondyloArthritis international Society recently defined early axial spondyloarthritis (axSpA) as a duration ≤2 years of axial symptoms. Previous studies have shown no significant difference in short‐term outcomes between early and established axSpA patients treated with biologic/targeted synthetic disease‐modifying anti ...
Annik Steimer, Jonas Brändli, Mauro Bachmann, Andrea Götschi, Claudia L. Rodrigues, Michael J. Nissen, Burkhard Möller, Kristina Bürki, Martin Wendiggensen, Simon Grosswiler, Michael Andor, Diana Dan, Frauke Förger, Sabine Adler, Diego Kyburz, Oliver Distler, Raphael Micheroli, Sofia Ramiro, Adrian Ciurea   +18 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source