Results 91 to 100 of about 226,083 (299)

Magneto-rotatory compressible couple-stress fluid heated from below in porous medium

open access: yesStudia Geotechnica et Mechanica, 2016
The study is aimed at analysing thermal convection in a compressible couple stress fluid in a porous medium in the presence of rotation and magnetic field.
Mehta Chander Bhan
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Effects of Couple Stress on the Growth Rate of Rayleigh- Taylor Instability at the Interface in a Finite Thickness Couple Stress Fluid

open access: yesJournal of Applied Fluid Mechanics, 2010
In this paper the effects of couple stress fluid on the control of Rayleigh-Taylor instability at the interface between a dense fluid accelerated by a lighter fluid is studied. A simple theory, based on fully developed approximations, is used to derive
N. Rudraiah, G. Chandrashekara
doaj  

A frictional Cosserat model for the flow of granular materials through a vertical channel

open access: yes, 1999
A rigid-plastic Cosserat model has been used to study dense, fully developed flow of granular materials through a vertical channel. Frictional models based on the classical continuum do not predict the occurrence of shear layers, at variance with ...
Mohan, L. Srinivasa   +2 more
core   +2 more sources

Thermodynamically consistent gradient elasticity with an internal variable

open access: yes, 2020
The role of thermodynamics in continuum mechanics and the derivation of the proper constitutive relations is a discussed subject of Rational Mechanics. The classical literature did not use the accumulated knowledge of thermostatics and was very critical ...
Ván, Peter
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Stryker Osteonics: Prosthetic Knee Joint [PDF]

open access: yes, 2008
We examine, within a simple bearing model of a knee joint that only consideres pure sliding, the effect of the presence of a small vertical hole in the load area on the fluid film properties.
Hjorth, P.G.   +5 more
core  

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