Results 71 to 80 of about 226,628 (293)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The postulations á la D'Alembert and á la Cauchy for higher gradient continuum theories are equivalent. A review of existing results [PDF]

, 2015
In order to found continuum mechanics, two different postulations have been used. The first, introduced by Lagrange and Piola, starts by postulating how the work expended by internal interactions in a body depends on the virtual velocity field and its ...
DELL'ISOLA, Francesco, DELLA CORTE, ALESSANDRO, Seppecher, P.   +2 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Flow of Two Immiscible Couple Stress Fluids between Two Permeable Beds

Journal of Applied Fluid Mechanics, 2016
The paper deals with the flow of two immiscible couple stress fluids between two homogeneous permeable beds. The flow is considered in two zones: zone I and II contain free flow of two immiscible couple stress fluids between two permeable porous beds ...
Dr. Srinivas Jangili, Ramana Murthy Venkata Josyula   +1 more
doaj  

Solitary vortex couples in viscoelastic Couette flow

, 1996
We report experimental observation of a localized structure, which is of a new type for dissipative systems. It appears as a solitary vortex couple ("diwhirl") in Couette flow with highly elastic polymer solutions.
A. C. Newell, A. Groisman, Alexander Groisman, G. I. Taylor, H. Riecke, K. Weissenberg, M. C. Cross, O. Lioubashevski, P. B. Umbanhowar, R. B. Bird, R. G. Larson, R. Haas, S. Fauve, Victor Steinberg   +13 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Singularities In Scalar-Tensor Cosmologies [PDF]

, 1997
In this article, we examine the possibility that there exist special scalar-tensor theories of gravity with completely nonsingular FRW solutions. Our investigation in fact shows that while most probes living in such a Universe never see the singularity ...
A. Lukas, A. Lukas, A. Sen, A. Sen, A. Shapere, A.A. Tseytlin, A.A. Tseytlin, A.A. Tseytlin, A.A. Tseytlin, A.A. Tseytlin, B. Allen, B.A. Campbell, B.A. Campbell, B.A. Campbell, C. Lovelace, C. Wetterich, C. Wetterich, C.G. Callan, C.G. Callan, C.M. Hull, D. Goldwirth, D. Gross, D. Luest, D.G. Boulware, E. Kiritsis, E. Witten, E.J. Copeland, E.J. Copeland, E.S. Fradkin, F. Larsen, G. Veneziano, G.T. Horowitz, H. Lu, I. Antoniadis, I. Antoniadis, I. Antoniadis, I. Antoniadis, I. Jack, J. Lauer, J. Maharana, J. Rizos, J.D. Barrow, K. Behrndt, K. Behrndt, K. Huang, K.A. Meissner, Keith A. Olive, M. Gasperini, M. Gasperini, M. Gasperini, M. Mueller, N. Kaloper, N. Kaloper, N. Kaloper, N. Kaloper, N.R. Stewart, Nemanja Kaloper, P. Binetruy, R. Brustein, R. Easther, R. Easther, R. Hagedorn, R. Poppe, R.C. Myers, R.H. Brandenberger, R.R. Metsaev, R.R. Metsaev, S. Deser, S. Kalara, S. Kalara, S. Weinberg, S.J. Rey, S.J. Rey, S.K. Rama, S.K. Rama, S.K. Rama, S.W. Hawking   +76 more
core   +3 more sources

Generalized Stokes' problems for an incompressible couple stress fluid

, 2013
{"references": ["V.K. Stokes, Couple stresses in fluids, 9(9) (1966), pp.1710-1715.", "V.K. Stokes, Theory of fluids with microstructure-An introduction, Springer Verlag, (1984).", "N.B. Naduvinamani, P.S. Hiremath, G. Gurubasavaraj, Squeeze film lubrication of a short porous journal bearing with Couple stress fluids, Tribology International, 34(11 ...
M.Devakar, T.K.V.Iyengar
openaire   +1 more source