Results 61 to 70 of about 226,628 (293)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Thermodynamics Analysis of Radiative Hydromagnetic Couple Stress Fluid through a Channel [PDF]

, 2017
This work applies second law of thermodynamics to analyse the effect of radiation on electrically conducting couple stress fluid through a channel. A constant magnetic field is introduced across the flow channel and the resulting Navier- Stokes and ...
Gbadeyan, J.A., Iyase, S.A ., Opanuga, A. A.   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Revisiting the thermodynamics of hardening plasticity for unsaturated soils [PDF]

, 2010
A thermodynamically consistent extension of the constitutive equations of saturated soils to unsaturated conditions is often worked out through the use a unique 'effective' interstitial pressure, accounting equivalently for the pressures of the ...
Alonso, Bear, Bear, Bishop, Bishop, Bolzon, Chateau, Collins, Coussy, Coussy, Coussy, Coussy, Coussy, Coussy, Cui, de Gennes, Fredlund, Gallipoli, Gens, Gray, Halphen, Hassanizadeh, Houlsby, Houlsby, Hutter, Jean Vaunat, Jean-Michel Pereira, Jennings, Khalili, Lemaitre, Lewis, Lewis, Li, Loret, Luong, Matyas, Murad, Olivier Coussy, Pereira, Roscoe, Roscoe, Schofield, Sheng, Sun, Sun, Vaunat, Wheeler, Wheeler   +47 more
core   +5 more sources

Rotatory Thermosolutal Convection in a Couple-Stress Fluid

Zeitschrift für Naturforschung A, 2009
Abstract The thermosolutal instability of couple-stress fluid in the presence of uniform vertical rotation is considered. Following the linearized stability theory and normal mode analysis, the dispersion is obtained. For the case of stationary convection, the stable solute gradient and rotation have stabilizing effects on the system ...
Pardeep Kumar, Mahinder Singh
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Influence of couple stress and magnetic fluid on the performance of step slider bearing

International Journal of Applied Mechanics and Engineering
This theoretical investigation delves into the performance of step slider bearings, considering the influence of couple stress and magnetic fluid as the lubricating medium.
Dipali K. Chauhan, JIMIT R. PATEL, G.M. Deheri   +2 more
doaj   +1 more source

Effect of Couple Stress Lubrication on Symmetric Hole-Entry Hybrid Journal Bearing

Tribology Online, 2017
The present study deals with capillary compensated symmetric hole-entry hybrid journal bearing under couple stress lubricant. Reynolds equation has been modified considering couple stress lubricant in the bearing system. The Galerkin’s Technique has been
Nathi Ram
doaj   +1 more source

Balancing torques in membrane-mediated interactions: Exact results and numerical illustrations

, 2007
Torques on interfaces can be described by a divergence-free tensor which is fully encoded in the geometry. This tensor consists of two terms, one originating in the couple of the stress, the other capturing an intrinsic contribution due to curvature.
B. Antonny, E. Kreyszig, H. Lodish, Jemal Guven, L. D. Landau, L. D. Landau, M. Do Carmo, M. Doi, Markus Deserno, Martin Michael Müller, O. Kratky, P. Biscari, P.-G. de Gennes, T. Frankel, V. I. Marchenko, W. Helfrich   +15 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source