Results 81 to 90 of about 380,039 (299)

A systematic review of iranian studies related to the effect of couple therapy methods on relationship disengagement [PDF]

open access: yesمجله علوم روانشناختی
Background: Relationship disengagement is the first step in the process that eventually leads to marital dissolution and is related to marital distress, poor communication, and mental health such as depression. Despite most of studies conducted regarding
Faezeh Salayani   +4 more
doaj  

Infant massage and quality of early mother-infant interactions: Are there associations with maternal psychological wellbeing, marital quality, and social support? [PDF]

open access: yes, 2017
Infant massage programs have proved to be effective in enhancing post-natal development of highly risk infants, such as preterm newborns and drug or HIV exposed children.
BOZZA, GIUSY   +4 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Service Participant Voices in Child Welfare, Children\u27s Mental Health, and Psychotherapy [PDF]

open access: yes, 2001
Service providers are becoming increasingly interested in hearing the views of service participants regarding issues of service delivery. This trend is viewed as progressive and sensitive to the many complex issues facing a diverse service participant ...
Coady, Nick   +2 more
core   +1 more source

Rejuvenation by cell reprogramming: A new horizon in gerontology [PDF]

open access: yes, 2018
The discovery of animal cloning and subsequent development of cell reprogramming technology were quantum leaps as they led to the achievement of rejuvenation by cell reprogramming and the emerging view that aging is a reversible epigenetic process. Here,
Brown, Oscar Alfredo   +5 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Comparison of the effectiveness of couple therapy based on acceptance and commitment (ACT), and gottman’s couple therapy on marital intimacy among conflicting couples

open access: yesمجله علوم روانشناختی, 2022
Background: Marital intimacy refers to the interaction between couples that leads to feelings of closeness, love and attention, and research has shown that it is a importanat factor in creating marital satisfaction. Despite the publication of the results
seyedrahman hosseini   +3 more
doaj  

Effectiveness of Self-Regulation Couple Therapy intervention on marital satisfaction and partner abuse (Non-physical)

open access: yesMediterranean Journal of Clinical Psychology, 2016
the aim of this research was to investigate effectiveness self-regulation couple therapy intervention on marital and partner abuse. in a semi-experimental with experimental and control group design, 24 couples were selected by convenient sampling method ...
Rasoul Heshmati   +3 more
doaj   +1 more source

Diagnosis and treatment of canine hypoadrenocorticism [PDF]

open access: yes, 2018
Canine hypoadrenocorticism (Addison’s disease), the ‘great pretender’ of internal medicine, is a disease that should be frequently considered as a differential diagnosis of several clinical presentations, albeit it is less commonly the actual cause of ...
Gunn, Eilidh   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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