Results 101 to 110 of about 6,973 (287)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
EnergiesThis paper presents a novel single-phase non-isolated bidirectional buck converter topology. The proposed converter uses a basic switching cell structure with a coupled inductor and an interleaving switching scheme.
Jamil Muhammad Khan +2 more
doaj +1 more source
Bidirectional DC–DC Converter with Coupled Inductor Fordc-Bus Regulation in Microgrid Applications [PDF]
, 2020 Robson Mayer +2 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
EnergiesThis article proposes a fully soft-switched coupled-inductor-based semi dual-active half-bridge (SDAHB) converter designed for wide voltage range and low power applications.
Liting Li +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
An Analytical Comparison of Interleaved Boost Converters with Different Inductor Configurations
Turkish Journal of Electrical Power and Energy SystemsThis study presents a comparative analysis of coupled and uncoupled inductors within an interleaved boost converter. The study includes the derivation of steady-state variables and magnetic equations for each inductor configuration.
Didar Ciftci +3 more
doaj +1 more source
An Improved Coupled-Inductor Impedance Source Network With More Freedom in Winding Match [PDF]
, 2020 Yuliang Ji +4 more
openalex +1 more source