Results 81 to 90 of about 2,413,185 (355)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
, 2016 Reliable powering of accelerator magnets requires reliable power converters and controls, able to meet the powering specifications in the long term. In this paper, some of the issues that will challenge a power converter controls engineer are discussed ...
King, Q.
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Interleaved ZVS DC‐DC converter with ultrahigh step‐down and flexible gain
IET Power ElectronicsThis paper proposes a novel non‐isolated ultrahigh step‐down interleaved DC‐DC converter with an extremely extended duty cycle based on the series capacitor and coupled‐inductor techniques. The proposed converter utilizes a three‐winding coupled inductor
Wahid Eskandary +3 more
doaj +1 more source
Design and analysis of an inductor-less cross-coupled voltage equalizer
Energy Reports, 2020 To equalize the imbalance in the state-of-charge (SoC) of lithium-ion cells, we propose a novel inductor-less cross-coupled voltage equalizer for series-connected batteries.
Kei Eguchi +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Modified A-Source Converter Operating at Lower Voltage Stress
IEEE Access, 2019 The coupled inductor based Z-source converter produces higher voltage gain with lower number of components count. In this paper, a new two winding mutually coupled inductor based Z-source DC-DC converter is proposed to boost the voltage gain.
Avneet Kumar +5 more
doaj +1 more source
A novel high step-up secondary side impedance source full-bridge converter [PDF]
, 2018 In order to suppress the voltage stress of semiconductor devices, and solve the reverse recovery problem of diodes by decreasing the duty cycle of switches, impedance source converters could be consider as a solution.
Martínez García, Herminio +2 more
core
Mitigation of Common mode Noise for PFC Boost Convertor by Balancing Technique [PDF]
, 2016 The PFC Boost Converter is an integral part of modern power supplies to improve power factor in electronic devices. The inherent problem associated with it is common mode (CM) Electromagnetic interference (EMI) noise arising due to the higher switching ...
Cobb, Jonathan E., Nasir,
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source