Results 61 to 70 of about 1,475,470 (297)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
DC-DC Converter with Coupled-Inductors Current-doubler [PDF]
A coupled-inductor current-doubler topology for a power converter has first and second rectifiers and first and second coupled inductors. Each coupled indicator has a main inductor inductively coupled with a secondary inductor.
Abu Qahouq, Jaber +2 more
core
This article proposed a new structure of nonisolated high step-up DC-DC converter based on a three-winding coupled inductor and voltage multiplier cells (VMCs) for renewable energy systems applications such as PV power generation.
Hafez Nouhi +2 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Non-Isolated High Step-Up DC/DC Converter With Coupled Inductor and Switched Capacitor
In this paper, a high-efficiency DC/DC converter with low voltage stress is designed for green power applications. The proposed non-isolated high step-up DC/DC converter combines the advantages of switched capacitors, coupling inductors, and voltage ...
Sang-Wha Seo +3 more
doaj +1 more source
A single-stage line-coupled half-bridge ballast with unity power factor and ripple-free input current using a coupled inductor is proposed. The proposed power-factor-correction circuit can achieve unity power factor and ripple-free input current using a ...
Do, HL +3 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source

