Results 71 to 80 of about 888,948 (305)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Interleaved ZVS DC‐DC converter with ultrahigh step‐down and flexible gain
IET Power ElectronicsThis paper proposes a novel non‐isolated ultrahigh step‐down interleaved DC‐DC converter with an extremely extended duty cycle based on the series capacitor and coupled‐inductor techniques. The proposed converter utilizes a three‐winding coupled inductor
Wahid Eskandary +3 more
doaj +1 more source
Design and analysis of an inductor-less cross-coupled voltage equalizer
Energy Reports, 2020 To equalize the imbalance in the state-of-charge (SoC) of lithium-ion cells, we propose a novel inductor-less cross-coupled voltage equalizer for series-connected batteries.
Kei Eguchi +3 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Modified A-Source Converter Operating at Lower Voltage Stress
IEEE Access, 2019 The coupled inductor based Z-source converter produces higher voltage gain with lower number of components count. In this paper, a new two winding mutually coupled inductor based Z-source DC-DC converter is proposed to boost the voltage gain.
Avneet Kumar +5 more
doaj +1 more source
High Step–Up Converter with Coupled Inductor
, 2017 W artykule przedstawiono przekształtnik podwyższający napięcie z dławikiem sprzężonym do zastosowań w systemach fotowoltaicznych. Dławik sprzężony oraz szeregowo umieszczony z nim kondensator umożliwia uzyskanie wysokiego współczynnika wzmocnienia ...
Harasimczuk, M.
core +1 more source
Electronic tuning of misaligned coils in wireless power transfer systems [PDF]
, 2014 The misalignment and displacement of inductively coupled coils in a wireless power transfer system (WPT) can degrade the power efficiency and limit the amount of power that can be transferred.
Whidborne, James F. +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source