Results 101 to 110 of about 1,475,470 (297)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Non-Isolated Ultra-High Step-Up DC-DC Converter Topology Using Coupled-Inductor-Based Inverting Buck-Boost and Voltage Multipliers

open access: yes
This paper introduces a non-isolated ultra-high voltage gain topology using the combination of the coupled-inductor-based inverting buck-boost converter (IBB) and voltage multiplier (VM) structure. In the proposed converter, an ultra-high step-up voltage
Van-Tinh Duong   +2 more
core   +1 more source

Inductance Dual Model and Control of Multiphase Coupled Inductor Buck Converter

open access: yes, 2020
This paper presents an inductance dual model for designing coupled inductors in multiphase buck converters. The model is derived as a topological dual of the reluctance model of a multiphase coupled inductor, yielding an inductance-based equivalent ...
Youssef Elasser   +9 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

A Switched-Coupled-Inductor Quasi-Z-Source Network With High Boost Capability

open access: yesIEEE Access
This paper proposes a new high gain quasi-Z-source network (qZSN) using a two-winding switched-coupled-inductor (SCL). By employing a two-winding SCL within the impedance network, the proposed topology offers high boost capability at low shoot-through ...
Mehran Moslehi Bajestan, Hamed Bizhani
doaj   +1 more source

Feasible evaluations of coupled multilayered chip inductor for POL converters

open access: yes, 2015
Point of load (POL) converters require a small size and high-efficiency performance for IT industrial applications. In addition, the interleaved technique, magnetic integration, and application of GaN FETs are well known as good approaches to satisfy ...
Martinez, Wilmar   +6 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Design of Coupled Inductor for Interleaved Boost Converter

open access: yes
This paper presents an analysis of coupled inductor for interleaved boost converter and the effect of coupled inductor on current ripple reduction and on load transient response time.
Kroičs, Kaspars   +2 more
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Coupled Inductor Design Methodology to Improve Energy Transfer Efficiency in Active Cell Balancing Circuit using Multi-Winding Coupled Inductor

open access: yes, 2019
This paper proposes a coupled inductor design of a cell balancing circuit using an inductor coupled by multiple windings. The coupling coefficient of the multiwinding inductor and the output capacitance of MOSFETs affect the energy transfer efficiency of
Kim, Myoungho   +2 more
core  

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