Results 51 to 60 of about 12,408 (253)

Coupled Fixed Point Theorems with Rational Type Contractive Condition in a Partially Ordered G-Metric Space

Journal of Mathematics, 2014
Coupled fixed point theorems for a map satisfying mixed monotone property and a nonlinear, rational type contractive condition are established in a partially ordered G-metric space.
K. Chakrabarti
doaj   +1 more source

Common coupled coincidence and coupled fixed point results in two generalized metric spaces [PDF]

Fixed Point Theory and Applications, 2011
AbstractIn this article, we prove the existence of common coupled coincidence and coupled fixed point of generalized contractive type mappings in the context of two generalized metric spaces. These results generalize several comparable results from the current literature.
Wasfı Shatanawi, Mujahid Abbas, Talat Nazır   +2 more
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Coupled Coincidence Fixed Point Theorems in S-Metric Spaces

IOSR Journal of Mathematics, 2014
In this paper we prove some coupled fixed point theorems in S-metric spaces.
Hans Raj, Nawneet Hooda
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Generalized compatibility in partially ordered metric spaces [PDF]

Surveys in Mathematics and its Applications, 2016
In this paper, we introduce the notion of generalized compatibility of a pair of mappings F,G:X× X→ X, where (X,d) is a partially ordered metric space.
Hassen Aydi, Manel Jellali
doaj  

Coupled fixed point theorems in complete metric spaces endowed with a directed graph and application

Open Mathematics, 2017
The purpose of this paper is to present some existence results for coupled fixed point of a (φ,ψ) —contractive condition for mixed monotone operators in metric spaces endowed with a directed graph.
Kir Mehmet, Yolacan Esra, Kiziltunc Hukmi   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Hybrid Coupled Fixed Point Theorems in Metric Spaces with Applications

Journal of Function Spaces, 2019
In this manuscript, using CLR property, coupled coincidence and common coupled fixed point results for two-hybrid pairs satisfying (F,φ)- contraction are demonstrated.
Muhammad Shoaib, Muhammad Sarwar, Thabet Abdeljawad   +2 more
doaj   +1 more source