Results 111 to 120 of about 2,303,991 (326)

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Steady-state stabilization due to random delays in maps with self-feedback loops and in globally delayed-coupled maps

, 2005
We study the stability of the fixed-point solution of an array of mutually coupled logistic maps, focusing on the influence of the delay times, $\tau_{ij}$, of the interaction between the $i$th and $j$th maps. Two of us recently reported [Phys. Rev. Lett.
A. S. Pikovsky, Arturo C. Martí, C. Masoller, J. Stoer, K. Kaneko, Marcelo Ponce, P. A. Horn   +6 more
core   +1 more source

An Illusion: “A Suzuki Type Coupled Fixed Point Theorem”

Abstract and Applied Analysis, 2014
We admonish to be careful on studying coupled fixed point theorems since most of the reported fixed point results can be easily derived from the existing corresponding theorems in the literature. In particular, we notice that the recent paper [Semwal and
Hamed H. Alsulami, Erdal Karapınar, Marwan A. Kutbi, Antonio-Francisco Roldán-López-de-Hierro   +3 more
doaj   +1 more source

FG-coupled fixed point theorems for contractive and generalized quasi-contractive mappings [PDF]

arXiv, 2016
In this paper we prove FG-coupled fixed point theorems for different contractive mappings and generalized quasi- contractive mappings in partially ordered complete metric spaces. We prove the existence of FG-coupled fixed points of continuous as well as discontinuous mappings. We give some examples to illustrate the results.
arxiv  

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Infrared stability of ABJ-like theories

, 2009
We consider marginal deformations of the superconformal ABJM/ABJ models which preserve N=2 supersymmetry. We determine perturbatively the spectrum of fixed points and study their infrared stability.
A Gustavsson, D Martelli, H-C Kao, J Bagger, J Bagger, JH Schwarz, LV Avdeev, LV Avdeev, M Benna, M Raamsdonk Van, Marco S. Bianchi, Massimo Siani, N Akerblom, O Aharony, O Aharony, S Hohenegger, Silvia Penati, SJ Gates, Y Hikida   +18 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

More CFTs and RG Flows from Deforming M2/M5-Brane Horizon

, 1999
Near-horizon geometry of coincident M2-branes at a conical singularity is related to M-theory on AdS4 times an appropriate seven-dimensional manifold X7.
Acharya, Ahn, Awada, Berkooz, Biran, Bourguignon, Breitenlohner, Breitenlohner, Castellani, Castellani, Changhyun Ahn, Cremmer, Cremmer, Cremmer, Cvetic, Cvetic, D'Auria, D'Auria, de Wit, de Wit, de Wit, de Wit, Duff, Duff, Duff, Englert, Freund, Girardello, Gubser, Jensen, Lu, Maldacena, Mezincescu, Morrison, Nicolai, Page, Page, Pope, Porrati, Soo-Jong Rey, Warner, Warner, Witten, Yasuda, Yasuda   +44 more
core   +1 more source

Fixed Point Structure for 3 dimensional rigid string [PDF]

arXiv, 1993
We show that the usual fixed point for 3-d rigid string with topological term appears to be a trivial one, consisting of two decoupled conformal field theories. We further argue that by involving an additional term allowed by symmetries and thus generated by RG, the theory appears to exhibit a new fixed point with expected symmetriy.
arxiv