Results 111 to 120 of about 856,874 (305)
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale+9 more
wiley +1 more source
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
Coupled fixed point theorems in complete metric spaces endowed with a directed graph and application
The purpose of this paper is to present some existence results for coupled fixed point of a (φ,ψ) —contractive condition for mixed monotone operators in metric spaces endowed with a directed graph.
Kir Mehmet+2 more
doaj +1 more source
Wess Zumino Couplings for Generalized Sigma Orbifold Fixed-points [PDF]
The Wess-Zumino couplings for generalized sigma-orbifold fixed-points are presented and the generalized GS 6-form that encoding the complete sigma-standard gauge-gravitational-non standard gauge anomaly and its opposite inflow is derived.
arxiv
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam+2 more
wiley +1 more source
Remarks on some coupled coincidence point results in partially ordered metric spaces
In this paper we have used a method of reducing coupled coincidence and coupled fixed point results in partially ordered metric spaces to the respective results for mappings with one variable, even obtaining (in some cases) more general theorems.
Stojan Radenović
doaj +1 more source
Common coupled coincidence and coupled fixed point results in two generalized metric spaces [PDF]
Wasfı Shatanawi+2 more
openalex +1 more source
Coupled fixed point theorems in partially ordered ε-chainable metric spaces [PDF]
In this paper, we introduce the notion of partially ordered {\epsilon}-chainable metric spaces and we derive new coupled fixed point theorems for uniformly locally contractive mappings on such spaces.
arxiv
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang+8 more
wiley +1 more source