Results 111 to 120 of about 1,462,493 (311)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Dimensionally reduced gravity theories are asymptotically safe

, 2003
4D Einstein gravity coupled to scalars and abelian gauge fields in its 2-Killing vector reduction is shown to be quasi-renormalizable to all loop orders at the expense of introducing infinitely many essential couplings.
't Hooft, Bakas, Bonneau, Breitenlohner, Breitenlohner, Brezin, Brezin, Brodbeck, Cremmer, Curci, Deser, Falkenberg, Fels, Fokas, Forgacs, Friedan, Galtsov, Goncalves, Graham, Helgason, Hikami, Howe, Keurentjes, Keurentjes, Klebanov, Lauscher, Lauscher, Lauscher, Loos, Lüscher, Max Niedermaier, Niedermaier, Osborn, Penati, Percacci, Percacci, Shore, Souma, Tseytlin, Weinberg, Zinn-Justin   +40 more
core   +2 more sources

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Some strong coupled coincidence and coupled best proximity results on complete metric spaces

Journal of Inequalities and Applications
In this paper, the concept of Wardowski’s class of contraction is integrated with that of g-coupling to define some F-contractive type g-couplings. We establish existence results for a coupled coincidence point, a strong coupled coincidence point, and a ...
Dakjum Eshi, Bipan Hazarika, Nipen Saikia, Sarah Aljohani, Sumati Kumari Panda, Ahmad Aloqaily, Nabil Mlaiki   +6 more
doaj   +1 more source

Coupled Fixed Point Theorems for Weak Contraction Mappings under F-Invariant Set

Abstract and Applied Analysis, 2012
We extend the recent results of the coupled fixed point theorems of Cho et al. (2012) by weakening the concept of the mixed monotone property. We also give some examples of a nonlinear contraction mapping, which is not applied to the existence of the ...
Wutiphol Sintunavarat, Yeol Je Cho, Poom Kumam   +2 more
doaj   +1 more source

Quantum criticality in Kondo quantum dot coupled to helical edge states of interacting 2D topological insulators

, 2012
We investigate theoretically the quantum phase transition (QPT) between the one-channel Kondo (1CK) and two-channel Kondo (2CK) fixed points in a quantum dot coupled to helical edge states of interacting 2D topological insulators (2DTI) with Luttinger ...
Brezin E, Chung-Hou Chung, Giamarchi T, Glazman L I, Gogolin A O, Hewson A C, Kim E, Kim M D, Kouwenhoven L, Kouwenhoven L, Salman Silotri   +10 more
core   +1 more source

An extension of Darbo fixed point theorem and its applications to coupled fixed point and integral equations

Filomat, 2014
In this paper, an extension of Darbo fixed point theorem is introduced. By applying our extension, we obtain a coupled fixed point theorem and a solution for an integral equation. The proofs of our results are based on the technique of measure of noncompactness.
Mohammad Bagher Ghaemi, Ayub Samadi
openaire   +3 more sources

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Coupled Fixed Point Theorems In 𝐺𝐛 - Metric Space

Indian Journal Of Science And Technology
Objective: The purpose of this research paper is to establish coupled common fixed-point theorems in Gb metric space. Methodology: By using integral type contractive conditions and weakly compatible mappings. Findings: Unique Common coupled fixed-point theorems are proved and two corollaries are stated.
K Varalakshmi, G Upender Reddy
openaire   +2 more sources

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source