Results 101 to 110 of about 34,975 (303)
Circular-geometry oscillators [PDF]
, 2004 5.3GHz 0.18μm CMOS circular-geometry oscillator exploits high Q of slab inductors. The oscillator draws 10mA from 1.4V with a phase noise of -147.3dBc/Hz at 10MHz offset. A second 5.4GHz circular-geometry VCO has a tuning range of 8% with phase noise of -
Aparicio, R., Hajimiri, A.
core +1 more source
, 2017 Eddy-current problems occur in a wide range of industrial and metallurgical applications where conducting material is processed inductively. Motivated by realising coupled multi-physics simulations, we present a new method for the solution of such ...
Beckstein, Pascal +2 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
IET Power ElectronicsMost coupled inductor‐based step‐up DC–DC converters encounter a significant voltage overshoot on their power switch due to the leakage inductance of the coupled inductor.
Mahnaz Izadi +2 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Energies, 2017 In this paper, a novel isolated bidirectional DC-DC converter is proposed, which is able to accomplish high step-up/down voltage conversion. Therefore, it is suitable for hybrid electric vehicle, fuel cell vehicle, energy backup system, and grid-system ...
Chih-Lung Shen +2 more
doaj +1 more source
Exceptional Points of Degeneracy Induced by Linear Time-Periodic Variation [PDF]
, 2019 We present a general theory of exceptional points of degeneracy (EPD) in periodically time-variant systems. We show that even a single resonator with a time-periodic component is able to develop EPDs, contrary to parity-time- (PT) symmetric systems that ...
Abdelshafy, AF +4 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Multimodal Resonance in Strongly Coupled Inductor Arrays [PDF]
IEEE Transactions on Instrumentation and MeasurementMagnetic resonance coupling (MRC) is widely used for wireless power transfer (WPT) applications, but little work has explored how MRC phenomena could be exploited for sensing applications. This paper introduces, validates and evaluates the unique multi-resonant phenomena predicted by circuit theory for over-coupled inductive arrays, and presents eigen ...
Robert R. Hughes +3 more
openaire +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source