Results 101 to 110 of about 37,925 (344)

A Novel Reversal Γ-Shape Coupled Inductor High-Step AC-AC Converter

Energies, 2018
This paper presents a novel reversal Γ-shape coupled inductor high-step AC-AC converter. This converter uses a reversal Γ-shape coupled inductor that consists of a two-winding coupled inductor for higher voltage gain.
Hongchen Liu, Xinsheng Zhang
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Automatic gain control system [PDF]

, 1969
Automatic gain control amplifier ...
Black, S. H.
core   +1 more source

Nonlinear resonant behavior of the dispersive readout scheme for a superconducting flux qubit

, 2006
A nonlinear resonant circuit comprising a SQUID magnetometer and a parallel capacitor is studied as a readout scheme for a persistent-current (PC) qubit.
A. Barone, A. H. Nayfeh, C. Bowick, F. Kouril, Janice C. Lee, Karl K. Berggren, L. D. Landau, Steven H. Strogatz, T. Holst, T. P. Orlando, William D. Oliver   +10 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Coupled Inductor Based Boost Microinverter With Dual Mode Time Sharing Operation for Renewable Energy Applications

IEEE Access
Household power conversion stages process significant amounts of power when they add up to form a microgrid. Microinverters are considered one of the best choices to utilize the renewable energy harvested power.
Fahad M. Alhuwaishel, Nabil A. Ahmed
doaj   +1 more source

Coupled‐inductor‐inverse high step‐up converter

IET Power Electronics, 2018
This study presents a novel high conversion gain converter with a tightly coupled‐inductor‐inverse for distributed generation system, where high conversion gain is regularly required. The new converter utilises coupled‐inductor‐inverse network for high conversion gain applications that is not presently comparable with the existing coupled inductor ...
Fei Li, Yu Yao, Zhi Wang, Hongchen Liu
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source