Results 141 to 150 of about 2,136,778 (329)

Single‐Switch High Step‐Up Quasi‐Z‐Source DC‐DC Converter With Low Switch Voltage Stress

The Journal of Engineering
High step‐up converters are commonly utilized to manage voltage level between the DC‐bus and low voltage input. The properties such as high‐voltage gain, continuous input current and low switch voltage stress are important for proper performance.
Karrar S. Faraj, Majid Delshad, Wameedh Riyadh Abdul‐Adheem, Mohammad Rouhollah Yazdani, Bahador Fani   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Non-Isolated High Step-Up DC-DC Interleaved Boost Converter Based on Coupled Inductors and Voltage Multiplier Cells

Energies
This work introduces a non-isolated high step-up dc-dc interleaved boost converter combining magnetic coupling and voltage multiplier cells (VMCs). The proposed topology features a transformer with two primary windings of equal turns, interconnected to ...
Thaís Carvalho Salvador, Rafael Mario da Silva, Waner Wodson Aparecido Goncalves Silva, Nedson Joaquim Maia, Fernando Lessa Tofoli, Enio Roberto Ribeiro   +5 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Design and Analysis of a New High Step-Up Converter Using Switched-Inductor-Capacitor Voltage Multiplier Cells for Photovoltaic Application

IEEE Journal of the Electron Devices Society
This article proposes a new high-gain converter to attain higher output voltage without coupled inductors. The operation of the proposed converter is examined under continuous conduction mode (CCM) and discontinuous conduction mode (DCM).
Ramachandran Rajesh, Natarajan Prabaharan, Eklas Hossain   +2 more
doaj   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Resonant Directly Coupled Inductors⁻Capacitors Ladder Network Shows a New, Interesting Property Useful for Application in the Sensor Field, Down to Micrometric Dimensions. [PDF]

Micromachines (Basel), 2018
D'Amico A, Santonico M, Pennazza G, Zompanti A, Scipioni E, Ferri G, Stornelli V, Salmeri M, Lojacono R.   +8 more
europepmc   +1 more source