Results 61 to 70 of about 22,197 (285)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Canonical circuit quantization with linear nonreciprocal devices

open access: yes, 2019
Nonreciprocal devices effectively mimic the breaking of time-reversal symmetry for the subspace of dynamical variables that they couple, and can be used to create chiral information processing networks. We study the systematic inclusion of ideal gyrators
DiVincenzo, D. P.   +3 more
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Topology of a Hybrid DC Circuit Breaker with Coupled Inductor-assisted Current Limiting [PDF]

open access: yesDianli jianshe
[Objective] With the increase in transmission capacity of DC grids, issues such as rapid rise of fault current, high amplitude, difficulty in breaking, and high cost arise in hybrid DC circuit breakers based on fully controlled power electronic devices ...
ZHANG Baoge, LI Guodong, HUANG Jiahong, CHANG Weishan
doaj   +1 more source

Efficient solution of 3D electromagnetic eddy-current problems within the finite volume framework of OpenFOAM

open access: yes, 2017
Eddy-current problems occur in a wide range of industrial and metallurgical applications where conducting material is processed inductively. Motivated by realising coupled multi-physics simulations, we present a new method for the solution of such ...
Beckstein, Pascal   +2 more
core   +1 more source

Design issues in CMOS differential LC oscillators [PDF]

open access: yes, 1999
An analysis of phase noise in differential cross-coupled inductance-capacitance (LC) oscillators is presented. The effect of tail current and tank power dissipation on the voltage amplitude is shown.
Hajimiri, Ali, Lee, Thomas H.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Study on an Improved Three-Winding Coupled Inductor Based DC/DC Boost Converter with Continuous Input Current

open access: yesEnergies, 2020
This paper proposes a novel high voltage conversion gain DC/DC boost converter for renewable energy applications and systems. The proposed converter utilizes a three-winding coupled inductor.
Amir Farakhor   +5 more
doaj   +1 more source

Waveform simulator Patent [PDF]

open access: yes, 1971
Sign wave generation simulator for variable amplitude, frequency, damping, and phase pulses for oscilloscope ...
Malmberg, J. H., Moore, C. D.
core   +1 more source

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