Results 81 to 90 of about 2,450,147 (304)

Soft‐Switching Non‐Isolated High Step‐Up DC‐DC Converter With Continuous Input Current for PV Application

IET Power Electronics
In this paper, a high step‐up DC‐DC boost converter is introduced, which utilises the coupled inductor and switched capacitor techniques to increase voltage gain, adjustable by changing the turn ratio of the coupled inductors.
Sadegh Heidari Beni, Sayyed Mohammad Mehdi Mirtalaei, Mahdi Shaneh, Tohid Nouri, Amir Baktash   +4 more
doaj   +1 more source

A zero voltage transition interleaved DC-DC converter with reduced voltage stress

Majlesi Journal of Electrical Engineering
This paper presents an interleaved converter designed to achieve a high voltage gain using a combination of coupled inductors and switched capacitors.
Hosein Talgini, Majid Delshad, Ramtin Sadeghi   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

A Zeroripple High Voltage Gain Convertor with Coupledinductors

Journal of Harbin University of Science and Technology, 2019
In this paper, a high voltage gain DC-DC converter with coupled inductor and ripple free is proposed for low voltage renewable energy generation system，such as photovoltaic, fuel cell and so on．The coupling inductor technology is introduced on the basis ...
LIANG Wen juan, TAN Guo dong, CHEN Hao, HU Xue feng   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Passivity Criterions of Networks With General Fractional Order Coupled Inductors

IEEE Access, 2019
Fractional order coupled inductor (FCI) was proposed recently which can enrich existing circuit element system. In this paper, the passivity conditions of FCI are discussed.
Guishu Liang, Zheng Qi, Long Ma, Chang Liu   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Very high step‐down coupled inductor two‐phase buck converter with single magnetic element and inherent clamp voltage capability

IET Power Electronics
This paper proposed a new two‐phase high step‐down DC–DC converter is proposed. This converter is derived from the two‐phase series‐capacitor converter. The proposed converter replaces the series capacitor with a new structure that integrates Valley‐Fill
Ahmad Ghamsari Esfahani, Ehsan Adib
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source