Results 81 to 90 of about 1,457,084 (256)

A Multiport/Multiphase DC/DC Converter with Coupled Inductors for Hybrid Energy Storage Systems Suitable for Aircraft Applications

Machines
This paper proposes a low weight hybrid battery–supercapacitor energy storage system interfaced with bidirectional DC/DC converters with high power/current capability for aircraft applications.
Abdullahi Abubakar, Christian Klumpner, Patrick Wheeler   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Butterfly Interleaving Winding Arrangements for Multiphase Coupled Inductors

, 2023
Multiphase coupled inductors in pulse-width modulated (PWM) converters benefit from the reduced steady-state current ripple and fast transient performance.
Li, Mingxiao, Liu, Yunfeng, Ouyang, Ziwei, Andersen, Michael A. E.   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A soft-switching inverting high step-down converter with a pair of coupled inductors and self-driven synchronous rectifier

, 2021
A soft-switching inverting high step-down converter with a pair of coupled inductors and self-driven synchronous ...
B Soleymani (13422600), Abbas Kouzani (13079637), H Farzanehfard (13422606), E Adib (13422603), MR Islam (9872390), MAP Mahmud (14347713), F Hosseinabadi (13422597)   +6 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

A Ćuk Converter Cell Balancing Technique by Using Coupled Inductors for Lithium-Based Batteries

Energies, 2019
In this paper, a c ´ uk converter balancing method by using a coupled inductor for lithium based batteries is investigated. The proposed circuit is an active balancing circuit that will equalize eight battery cells in a series.
Ali Farzan Moghaddam, Alex Van den Bossche   +1 more
doaj   +1 more source

High Power Factor Single-Stage ZVS Charger with Coupled Inductors

, 2014
[[abstract]]This paper presents a zero voltage switching (ZVS) single-stage charger with power factor correction (PFC) based on an asymmetrical half-bridge topology and coupled inductors.
J.-C. Hung;T.-F. Wu;S.-Y. Tseng;Y.-M. Chen
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source