Results 91 to 100 of about 1,457,084 (256)

Single-Phase Multilevel Inverter With a Coupled Inductor

open access: yesIEEE Access
Multilevel inverters have become indispensable components in various power electronic applications, particularly in medium-and high-voltage scenarios. This paper introduces a novel single-phase seventeen-level inverter design that utilizes three DC sources and a coupled inductor, resulting in a reduced size and cost.
Noor Jaafar Jawad Alradhawi   +3 more
openaire   +3 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Benefits of the Coupled Inductors Combined Cuk-SEPIC (CI-CCS) Converter [PDF]

open access: yes, 2018
An enhanced DC-DC converter is proposed in this paper, based on the combination of the Cuk and SEPIC converters. This converter uses a single switching node which is common to both Cuk and SEPIC energy transfer stages. The converter uses only one switch,
Flack, T   +7 more
core   +3 more sources

Multimodal Resonance in Strongly Coupled Inductor Arrays

open access: yesIEEE Transactions on Instrumentation and Measurement
Magnetic resonance coupling (MRC) is widely used for wireless power transfer (WPT) applications, but little work has explored how MRC phenomena could be exploited for sensing applications. This paper introduces, validates and evaluates the unique multi-resonant phenomena predicted by circuit theory for over-coupled inductive arrays, and presents eigen ...
Robert R. Hughes   +3 more
openaire   +2 more sources

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

A BAIDIRECTIONAL DC–AC CONVERTER BASED ON AN ASYMMETRIC INVERTER FOR HYBRID ENERGY STORAGE SYSTEMS

open access: yesТехнічна електродинаміка
This paper presents the analysis of electromagnetic processes in a bidirectional DC-AC converter based on an asymmetric inverter with magnetically coupled inductors, as well as the determination of its parameters aimed at improving energy efficiency. The
D.V. Martynov   +2 more
doaj   +1 more source

Low Voltage Multi-level Converters using Split-wound Coupled Inductors [PDF]

open access: yes, 2013
In low-voltage applications, an alternative approach to multi-level capacitorbased converters can be obtained by interleaving the switching of two converters across split-wound coupled inductors.
Ewanchuk, Jeffrey
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

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