Results 61 to 70 of about 379,372 (352)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Amplified Fiber-Optic Recirculating Delay Lines [PDF]

open access: yes, 1994
Experimental and theoretical results on single- and double-amplified recirculating delay lines are presented. One of our aims is to emphasize their application as filters, showing a wide flexibility of design.
Vizoso, Beatriz   +6 more
core   +1 more source

Coupled Transmission Lines as Impedance Transformer [PDF]

open access: yesIEEE Transactions on Microwave Theory and Techniques, 2007
A theoretical investigation of the use of a coupled line section as an impedance transformer is presented. We show how to properly select the terminations of the coupled line structures for effective matching of real and complex loads in both narrow and wide frequency ranges.
Jensen, Thomas   +3 more
openaire   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Micrometer Scale Resolution Limit of a Fiber-Coupled Electro-Optic Probe

open access: yesSensors, 2019
We present the practical resolution limit of a fine electrical structure based on a fiber-coupled electro-optic probing system. The spatial resolution limit was experimentally evaluated on the sub-millimeter to micrometer scale of planar electrical ...
Young-Pyo Hong   +6 more
doaj   +1 more source

A Novel Wideband Bandpass Filter Using Coupled Lines and T-Shaped Transmission Lines with Wide Stopband on Low-Cost Substrate

open access: yes, 2016
This paper presents the design, simulation, fabrication and measurement of a wideband bandpass filter with wide stopband performance operating at 3.5 GHz. The proposed filter consists of two parallel coupled lines (T-PCL) centred by T-inverted shape. The
Lahcen Yechou   +4 more
semanticscholar   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Direct design method for wideband quadruplet and higher‐order bandpass filters with a pair of transmission zeros based on explicit design formulas

open access: yesIET Microwaves, Antennas & Propagation
This paper presents a direct design approach and explicit design formulas for a wideband quadruplet bandpass filter with a pair of transmission zeros. A filter can be designed based on a filter schematic composed of only transmission lines and a short ...
Juseop Lee   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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