Results 51 to 60 of about 189,032 (295)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Comparing the Effectiveness of Gottman Couple Therapy with Datilio Couple Therapy on Improving the Sexual Satisfaction among Couples

open access: yesSalāmat-i ijtimā̒ī, 2019
Background and Objectives: Marital relationship is one of the most stable interpersonal relationships and its impact on individuals and society is more than any other relationship.
Azadeh Mahvelati   +2 more
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Expectations and Experiences of Couples Receiving Therapy Through Videoconferencing: A Qualitative Study

open access: yesFrontiers in Psychology, 2020
Videoconferencing is an emerging medium through which psychological therapy, including relationship interventions for couples, can be delivered. Understanding clients’ expectations and experiences of receiving therapy through this medium is important for
Andrea Kysely   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

'I think you understand me' : studying the associations between actual, assumed, and perceived understanding within couples [PDF]

open access: yes, 2019
The current study examined the associations between actual, assumed, and perceived understanding and partners' levels of dyadic adjustment. One hundred fifty-two couples provided questionnaire data (assumed and perceived understanding), participated in a
Gistelinck, Fien   +3 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Assessment of questionnaires measuring quality of life in infertile couples: A systematic review [PDF]

open access: yes, 2013
Background: Infertility has potentially inappropriate effects on quality of life in infertile couples. Various general and specific questionnaires have been structured for assessing different aspects of quality of life in infertile men, women, or couples.
Keramat, A.   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Comparing the effectiveness of behavioral couple therapy and based on acceptance and commitment therapy on alexithymia in maladjusted couples

open access: yesمجله علوم روانشناختی, 2019
Background: Alexithymia is one of the factors that causes Maladjustment and conflict between couples. The effectivenss of couples therapy and acceptance therapy on various variables in couples' lives has been confirmed, but the key question is which ...
fatemeh hooshyar   +4 more
doaj  

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