Results 31 to 40 of about 109,177 (261)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Coupling Coordination of Coordinated Development Level Between Resource and Environment
Abstract Environmental problems are drawing more and more attention from all sectors. Considering China’s current development background, it is very important to research the coordinated development level of resources and environment. This paper constructs the coupling index system of resource and environment. Then, we analyze the spatio-
Hua Gao, Qian Han
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
[Objective] The temporal and spatial characteristics and coupling coordination relationship of the productive-living-ecological function of land space for the ecological corridor of the Yangtze-Huaihe River were studied in order to provide a scientific ...
Anqin Li, Dan Wang, Yong Zhu
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
In order to clarify the degree of coupling and coordination of land intensive use,economic development and environmental and ecological effects,based on the coupling and coordination model,Shaanxi Province in the Western Development City Cluster was ...
MIN Yilan, CHEN Yan, LI Lutang
doaj
The coordinated development of urbanization and atmospheric environment is of great significance for improving the quality of urbanization and solving air pollution problems in the Bohai Rim region.
Nie Chengjing +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The spatial imbalance between population growth, land use and housing supply is the central issue for regional coordination of urban agglomeration in China.
Qingshan Kong +4 more
doaj +1 more source
Collective Coordinates of the Skyrme Model Coupled with Fermions [PDF]
The problem of construction of fiber bundle over the moduli space of the Skyrme model is considered. We analyse an extension of the original Skyrme model which includes the minimal interaction with fermions. An analogy with modili space of the fermion-monopole system is used to construct a fiber bundle structure over the skyrmion moduli space.
openaire +3 more sources

