Results 51 to 60 of about 109,177 (261)

Investigation of Dynamic Coupling Coordination between Urbanization and the Eco-Environment—A Case Study in the Pearl River Delta Area

Land, 2021
The interaction between urbanization and the eco-environment is usually viewed as an effect–feedback framework. Its coupling system is composed of urbanization and eco-environment subsystems.
Caige Sun, Shengyong Zhang, Chuncheng Song, Jianhui Xu, Fenglei Fan   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Evaluation of national fitness and national health development and coupling and coordination in 11 provinces and cities in Eastern China.

PLoS ONE
Under the influence of development strategies with regard to national fitness and health in China, the interactive development between national fitness and national health is becoming increasingly strong.
Dongxu Lin, Haixia Wang, Jinfu Xu, Lin Niu   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Coupling Coordination and Spatial Evolution of Sustainable Tourism-Innovation-Environment System: Evidence in China

SAGE Open, 2023
Coupling tourism development (TD), scientific and technological innovation (ST), and ecological environment (EE) is crucial to regional sustainable development, and it is necessary to explore the spatial and temporal characteristics. The study constructs
Zhijun Chen, Suting Zhao, Meiju Wu
doaj   +1 more source

The generator coordinate method for a reaction coordinate coupled to a harmonic oscillator bath [PDF]

The Journal of Chemical Physics, 1998
This paper investigates the usefulness of the generator coordinate method (GCM) for treating the dynamics of a reaction coordinate coupled to a bath of harmonic degrees of freedom. Models for the unimolecular dissociation and isomerization process (proton transfer) are analyzed.
Cruz, FFDS, Ruzzi, M., Schmidt, ACK
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The spatio-temporal characteristics and dynamic evolution of coupling and coordinated development of innovation factor allocation and green economy in China

Frontiers in Environmental Science
IntroductionMeasuring the coupling coordination degree between the innovation factor allocation system and the green economy development system, and deeply exploring the changing trends in the coupling coordination between innovation factors allocation ...
Kangshun Geng, Xiaotao Zhang, Hong Jiang, Zixuan Zhuang   +3 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source