Results 71 to 80 of about 110,100 (307)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Examining the Coupling Coordinated Relationship between Urban Industrial Co-Agglomeration and Intensive Land Use

Land, 2021
Exploring the dynamic relationship and coupling coordination between urban industrial co-agglomeration and intensive land use is vital to ensure high-quality urban development.
Qunxi Gong, Gengxuan Guo, Sipan Li, Xuedong Liang   +3 more
doaj   +1 more source

Criteria for classification of coupling coordination levels.

, 2023
Criteria for classification of coupling coordination levels.
Hongyu Ma (212546), Kaihang Ou (16877172), Xufan Zhou (16877181), Jing Xiong (218613), Shiqiao Fang (16877169), Lifang Han (16877178), Rongmei Teng (16877175)   +6 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

The generator coordinate method for a reaction coordinate coupled to a harmonic oscillator bath [PDF]

The Journal of Chemical Physics, 1998
This paper investigates the usefulness of the generator coordinate method (GCM) for treating the dynamics of a reaction coordinate coupled to a bath of harmonic degrees of freedom. Models for the unimolecular dissociation and isomerization process (proton transfer) are analyzed.
Cruz, FFDS, Ruzzi, M., Schmidt, ACK
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The spatio-temporal characteristics and dynamic evolution of coupling and coordinated development of innovation factor allocation and green economy in China

Frontiers in Environmental Science
IntroductionMeasuring the coupling coordination degree between the innovation factor allocation system and the green economy development system, and deeply exploring the changing trends in the coupling coordination between innovation factors allocation ...
Kangshun Geng, Xiaotao Zhang, Hong Jiang, Zixuan Zhuang   +3 more
doaj   +1 more source

Results of coupling coordination influence factor detection.

, 2022
Results of coupling coordination influence factor detection.
Fengge Yao (12988315), Jiayuan Liang (5817173), Liqing Xue (13176086)   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Coupling Coordination and Influencing Factors of Urbanization and Ecological Resilience in the Yangtze River Delta Urban Agglomeration, China

Land
Twenty-six cities in the Yangtze River Delta urban agglomeration were taken as the research object, and this study comprehensively evaluated urbanization quality and ecological resilience from 2005 to 2020.
Qiaoli Chang, Yuying Sha, Yi Chen
doaj   +1 more source