Results 61 to 70 of about 1,716,980 (301)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Coordination of the legs of a slow-walking cat [PDF]

, 1992
Cruse H, Warnecke H. Coordination of the legs of a slow-walking cat. Experimental Brain Research. 1992;89(1):147-156.On the basis of behavioural studies the influences that coordinate the movement of the legs of a slowly walking cat have been ...
Warnecke, H., Cruse, Holk
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Degree of coordination in market-coupling and counter-trading [PDF]

Cross-border trade remains a contentious issue in the restructuring of the European electricity market. Difficulties stem from the lack of a common market design, the separation between energy and transmission markets and the insufficient coordination ...
OGGIONI, Giorgia, SMEERS, Yves
core   +2 more sources

Temporal and Spatial Pattern and Its Formation Mechanism of the Coupling Coordination Between Urbanisation and Water Resources System in Yunnan Province

Shuitu baochi yanjiu, 2022
In order to reveal the inherent laws of the coupling coordination state between urbanisation and water resources system, Yunnan Province was taken as an object of study.
CHEN Xicai, PENG Yanmei, DUAN Zhengyang, PEI Ziyu, WANG Xueliang, XU Yongtao, PAN Yujun   +6 more
doaj  

Investigation of Dynamic Coupling Coordination between Urbanization and the Eco-Environment—A Case Study in the Pearl River Delta Area

Land, 2021
The interaction between urbanization and the eco-environment is usually viewed as an effect–feedback framework. Its coupling system is composed of urbanization and eco-environment subsystems.
Caige Sun, Shengyong Zhang, Chuncheng Song, Jianhui Xu, Fenglei Fan   +4 more
doaj   +1 more source

Coordination-Controlled C–C Coupling Products via ortho-Site C–H Activation

, 2019
The coordination-restricted ortho-site C–H bond activation and dehydrogenative homocoupling of 4,4′-(1,3-phenylene)­dipyridine (1,3-BPyB) and 4,4′-(1,4-phenylene)­dipyridine (1,4-BPyB) on different metal surfaces were studied by a combination of ...
Na Li (6550), Sumit Beniwal (1301532), Chao Li (145513), Sabine Maier (262348), Na Xue (1737205), Nemanja Kocić (6320141), Qiang Xue (6320147), Shimin Hou (2669935), Xue Zhang (166886), Ruoning Li (6320144), Krisztián Palotás (1361190), Yongfeng Wang (139179), Hao Wang (39217)   +12 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Evaluation of national fitness and national health development and coupling and coordination in 11 provinces and cities in Eastern China.

PLoS ONE
Under the influence of development strategies with regard to national fitness and health in China, the interactive development between national fitness and national health is becoming increasingly strong.
Dongxu Lin, Haixia Wang, Jinfu Xu, Lin Niu   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source