Results 81 to 90 of about 110,100 (307)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Research on the coupling measurement of medical education and health resource allocation under the background of healthy China

BMC Medical Education
Objective To analyze the coupling and coordination level of medical education and health resource allocation in China, and to provide scientific basis for promoting the high-quality development of medical education and the efficient allocation of health ...
Chen Jieting, Zhu Yan, Song Zhilong, Li Siyuan, Wu Xiangwei   +4 more
doaj   +1 more source

Phase Transitions for a Collective Coordinate Coupled to Luttinger Liquids

Physical Review Letters, 2013
We study various realizations of collective coordinates, e.g. the position of a particle, the charge of a Coulomb box or the phase of a Bose or a superconducting condensate, coupled to Luttinger liquids (LL) with N flavors.
Horovitz Baruch, Giamarchi Thierry, Le Doussal Pierre   +2 more
openaire   +5 more sources

Coordination of the legs of a slow-walking cat

, 1992
Cruse H, Warnecke H. Coordination of the legs of a slow-walking cat. Experimental Brain Research. 1992;89(1):147-156.On the basis of behavioural studies the influences that coordinate the movement of the legs of a slowly walking cat have been ...
Warnecke, H., Cruse, Holk
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Coupling Coordination Degree of Land, Ecology, and Food and Its Influencing Factors in Henan Province

Agriculture
Studying the spatiotemporal evolution characteristics of the coupling coordination of the land–ecology–food system (LEF) aids in promoting green agricultural development and regional resource management.
Xian Yang, Donghao Li, Miao Wang, Xinjie Shi, Yong Wu, Ling Li, Wenpei Cai   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Analysis of the coupling coordination spatial network and driving factors of urban pollution and carbon emissions in China

Environmental Research Communications
With the acceleration of urbanization and industrialization, the issues of urban pollution emissions and carbon emissions have become increasingly prominent. The coupling coordination relationship between pollution emissions and carbon emissions has also
Qingfeng Luo, Jingyuan Wang
doaj   +1 more source

Spatio-temporal characteristics and coupling coordination relationship between industrial green water efficiency and science and technology innovation: A case study in China

Ecological Indicators
To achieve the objective of high-quality development, an in-depth examination of the coupling coordination relationship between industrial green water and science and technology (S&T) innovation is essential.
Fuhua Sun, Jiayi Guo, Xin Huang, Zelong Shang, Bu Jin   +4 more
doaj   +1 more source

Two coupling mechanisms which determine the coordination of ipsilateral legs in the walking crayfish

, 1986
Cruse H, Müller U. Two coupling mechanisms which determine the coordination of ipsilateral legs in the walking crayfish. The Journal of Experimental Biology.
Cruse, Holk, Müller, Uwe
core